无创与有创机械通气治疗呼吸窘迫综合征早产儿解脲支原体感染的疗效观察

沈向梅1 ，张晶樱2

（1.西安医学院第一附属医院，陕西 西安 710077；2.浙江大学附属儿童医院，浙江 杭州，310003）

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摘要：

目的 回顾性分析无创及有创机械通气治疗呼吸窘迫综合症（RDS）早产儿解脲脲原体（UU）感染的疗效。方法 选择 2011年6月至2013年12月收治的新生儿呼吸窘迫综合征，且符合机械通气的早产儿60例，随机选取30例诊断为RDS早产儿UU 感染的患儿作为UU感染组，其中15例使用无创机械通气（NCPAP）治疗作为A组，15例使用有创机械通气治疗作为B组；30例诊断为RDS早产儿非UU 感染的患儿作为非UU感染组，其中15例使用NCPAP 治疗作为C组，15例使用有创机械通气作为D组。比较UU 感染组各组与非UU 感染组机械通气时间与胸片恢复时间。结果 A组体重与C组体重比较，差异无统计学意义（P>0.05）；A组NCPAP 治疗时间与C组治疗时间比较，差异无统计学意义（P>0.05）；A组胸片恢复时间与 C组胸片恢复时间比较，差异无统计学意义（P>0.05）；B组体重与D组体重比较，差异无统计学意义（P>0.05）；B组有创机械 通气治疗时间与D 组治疗时间比较，差异有统计学意义（P<0.05）；B组胸片恢复时间与D组胸片恢复时间，差异有统计学意义（P<0.05）。结论 无创机械通气治疗RDS早产儿UU感染在机械通气使用时间及胸片恢复时间上优于有创机械通气。

关键词：吸窘迫综合症;无创机械通气;新生儿肺透明膜病;解脲支原体

中图分类号：R722.1文献标志码：A文章编号：2096-1413(2017)12-0109-03

Curative effect observation of noninvasive and invasive mechanical ventilation in treatment of respiratory distress syndrome premature solution ureaplasma urealyticum infection
SHEN-Xiang-mei 1, ZHANG-Jing-ying 2
(1. the First Affiliated Hospital of Xi an Medical University, Xi an 710077; 2. the Affiliated Children s Hospital of

Zhejiang University, Hangzhou 310003, China)

ABSTRACT: Objective To explore the curative effect of Noninvasive and invasive mechanical ventilation in treatment of respiratory distress syndrome (RDS) premature solution ureaplasma urealyticum (UU) infection. Methods Sixty patients with neonatal respiratory distress syndrome who were treated with mechanical ventilation from June 2011 to December 2013 were selected as research objects. Thirty patients diagnosed with RDS premature UU infection of children as UU infection group, and 15 cases using NCPAP therapy named group A, while 15 cases with invasive mechanical ventilation treatment named group B. Thirty patients diagnosed with RDS premature of non-UU infection children as non-UU infection group, and 15 cases using NCPAP therapy named group C, while 15 cases with invasive mechanical ventilation treatment named group D. The mechanical ventilation time and chest radiograph recovery time of the two groups were compared. Results The weight of group A and group C has no statistically significant difference (P>0.05); NCPAP therapy time of group A and group C has no statistically significant difference (P>0.05); Chest radiograph recovery time of group A and group C, h as no statistically significant difference (P>0.05); the weight of group B compared with group D, has no statistically significant difference (P>0.05); invasive mechanical ventilation treatment time of group B and group D has statistically significant difference (P<0.05); the X-ray sternum recovery time of group B and group D has statistically significant difference (P<0.05). Conclusion Non -invasive mechanical ventilator treatment of RDS preterm infants UU infection in mechanical ventilation and chest radiotherapy recovery time is superior to invasive mechanical ventilation.
KEYWORDS: respiratory distress syndrome; noninvasive mechanical ventilation; neonatal pulmonary hyaline membrane disease; ureaplasma urealyticum.

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