左旋甲状腺素片治疗妊娠期甲状腺功能减退对子代的影响
周琴,刘晓瑛,宋媛,叶侃,孔锐
(苏州市立医院本部,江苏 苏州,215000)
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摘要:
目的 探讨左旋甲状腺素片治疗妊娠期甲状腺功能减退对子代体格发育与神经行为发育的影响。方法 选取于我院产科门诊产检的266例产妇,分为治疗组和对照组,孕期甲状腺功能减退并使用左旋甲状腺素片治疗的61 例产妇为治疗组, 无甲状腺功能减退的205例孕妇为对照组,对两组后代在42天龄及6月龄时进行体格生长及神经行为测定。结果 两组产 妇分娩方式比较,差异有统计学意义(P<0.05)。两组子代出生体重和身长比较,差异无统计学意义(P>0.05);两组子代在42天龄和6月龄时的体格发育指标及神经行为发育情况比较,差异无统计学意义(P>0.05)。结论 使用左旋甲状腺素片治疗孕期甲状腺功能减退,可使孕期甲状腺素维持在正常水平,且不影响子代的生长发育与神经行为发育。
关键词:甲状腺功能减退;左旋甲状腺素片;子代生长发育;神经行为发育
中图分类号:R714.256文献标志码:A文章编号:2096-1413(2017)12-0139-02
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