脑血管造影及供血动脉栓塞在富血供脑膜瘤手术中的应用效果

杨震，胡焱，徐东为，闫忠军

（第四军医大学附属唐都医院，陕西 西安，710038）

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摘要：

目的 探讨脑血管造影及供血动脉栓塞应用于富血供脑膜瘤手术中的临床效果。方法 选取2014年6月至2016年6月在我院治疗的68例富血供脑膜瘤患者为研究对象，随机分为对照组和试验组，各34 例。对照组患者术前未行脑血管造影及供血动脉栓塞，试验组患者术前行脑血管造影及供血动脉栓塞。比较两组患者的临床效果。结果 治疗后，试验组患者的手术时间、术中出血量及并发症发生率明显优于对照组（P<0.05）；试验组患者的Ⅰ、Ⅱ、Ⅲ、Ⅳ级的肿瘤切除程度明显优于对照组（P<0.05）；两组患者的各GOS评分发生率比较，差异无统计学意义（P>0.05）。结论 脑血管造影及供血动脉栓塞应用于富血供脑膜瘤手术中，可提高肿瘤切除程度，减少术中出血量，并提高了患者的生活质量。

关键词：脑血管造影；供血动脉栓塞；富血供脑膜瘤

中图分类号：R739.45文献标志码：A文章编号：2096-1413(2017)13-0052-02

Application effect of cerebral angiography and blood supply artery embolization in large-hypervascula

meningioma operation

YANG Zhen, HU Yan, XU Dong-wei, YAN Zhong-jun
(the Fourth Military University Affiliatted Tangdu Hospital, Xi an 710038, China)

ABSTRACT: Objective To investigate the clinical effect of cerebral angiography and blood supply artery embolization in the treatment of large-hypervascula meningioma operation. Methods Sixty-eight cases of patients with large-hypervascula meningioma operation admitted in our hospital from June 2014 to June 2016 were selected and randomly divided into control group and experimental group, with 34 cases in each group. The control group wasn`t given cerebral angiography and blood supply artery embolization before operation, while the experimental group received cerebral angiography and blood supply artery embolization before operation. The clinical effects of two groups were compared. Results After treatment, the operation time, blood loss and complication rate of the experimental group were better than those of the control group (P<0.05). The degree of Ⅰ,Ⅱ,Ⅲ,Ⅳ tumor resection of the experimental group was better than that of the control group (P<0.05). There was no significant difference in the incidence of each GOS scores of the two groups (P>0.05).Conclusion Cerebral angiography and blood supply artery embolization in the treatment of large-hypervascula meningioma operation can improve the degree of tumor resection, reduce the bleeding loss and improve the patients` quality of life.

KEYWORDS: cerebral angiography; arterial embolization; large-hypervascula meningioma

参考文献：
[1] 王志明,袁进国,曹藏柱,等.老年患者大型富血供脑膜瘤手术治疗36例临床分析[J].中国肿瘤临床与康复,2009,16(5):436-437.

[2] 冉启山,王飞,耿世经,等.脑血管造影在富血供脑膜瘤手术切除中的意义(附16例报告)[J].遵义医学院学报,2008,31(3):280-281.
[3] PANAGOPOULOS AT,LANCELLOTTI CL,VEIGA JC,et al.Expression of cell adhesion proteins and proteins related to angiogenesis and fatty acid metabolism in benign, atypical, and anaplastic meningiomas[J]. J Neurooncol,2008,89(1):73-87.
[4] 朱晓波.岩斜坡富血供脑膜瘤外科治疗中显微解剖、瘤周水肿和血管新生的研究[D].长春:吉林大学,2014.
[5] 谭平国,李则群,蔡望青,等.人脑胶质瘤组织中nm23与PCNA的表达及其意义[J].癌症,2003,22(10):1077-1080.
[6] XIANG Y,YAO H,WANG S,et al.Prognostic value of survivin and Livin in nasopharyngeal carcinoma[J].Laryngoscope,2006,116(1):126-130.

[7] 黄穗乔,梁碧玲,谢榜昆,等.富血供脑膜瘤的MRI表现和诊断—附126例分析[J].癌症,2004,23(11):1329-1333.
[8] 袁军,吴昱,陈曦,等.参附注射液对富血供脑膜瘤手术后意识和认知功能的影响[J].医药导报,2011,30(9):1167-1169.
[9] 徐爱国,江超武,纳玉萍,等.上颌窦原发性异位富血供脑膜瘤1例并文献复习[J].临床耳鼻咽喉头颈外科杂志,2011,25(14):667-668.
[10] 郑晓涛,余林,李新春,等.侧脑室富血供脑膜瘤的MRI诊断(附16例病例)[J].中国CT 和MRI 杂志,2011,9(4):8-10.
[11] 聂松义,李华虹,刘乙辉.哈尔滨医科大学附属第二医院成功实施动脉瘤合并富血供脑膜瘤切除术[N].中国医药报,2009.
[12] 张婧娴,刘玉娥,唐文恒,等.富血供巨大富血供脑膜瘤术前栓塞的临床应用[J].实用医学影像杂志,2010,11(4):263-266.
[13] 李真保,徐善水,方兴根,等.老年人脑膜瘤的脑血管造影及术前栓塞治疗[J].临床神经外科杂志,2007,4(1):7-9.
[14] 周政,刘俊,杨辉,等.术前超选择性栓塞高血运脑膜瘤的临床意义[J].介入放射学杂志,2004,13(5):390-392.
[15] 宗登伟,郭晨阳,黎海亮,等.富血供巨大脑膜瘤全脑血管造影及术前栓塞疗效观察[J].介入放射学杂志,2014,23(3):195-197.