肺炎支原体肺炎患儿血清降钙素原和C-反应蛋白水平变化的临床意义

黄婷，郝海燕，王静，荣强全，全瑶

（高淳人民医院儿科，江苏 南京，211300）

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摘要：

目的 探讨血清降钙素原（PCT）、C-反应蛋白（CRP）水平变化在肺炎支原体肺炎患儿诊断中的意义。方法 选取我院收治的支原体肺炎患儿56例（观察组）、细菌性肺炎患儿54例（对照A组）、病毒性肺炎患儿55例（对照B组）及健康体检儿童50例（正常组），观察组按病程分为急性期组（40例）和恢复期组（16例）。检测四组研究对象入院后24h的血清PCT、CRP水平及阳性率及急性期组和恢复期组患儿血清PCT、CRP水平。结果 对照A、B组和观察组的血清CRP、PCT水平明显高于正常组（P<0.05）；对照A组血清CRP、PCT水平显著高于观察组和对照B组（P<0.05）；观察组CRP水平显著高于对照B组（P<0.05）。对照A组PCT、CRP阳性率明显高于对照B组和观察组（P<0.05）。急性期组和恢复期组患儿PCT、CRP水平均明显高于正常组（P<0.05）。结论 在肺炎支原体肺炎患儿的临床诊断上，联合检测血清PCT、CRP水平可与细菌性肺炎等有效鉴别，为临床治疗提供有价值的参考。

关键词：肺炎支原体肺炎；血清降钙素原；C-反应蛋白

中图分类号：R725.6文献标志码：A文章编号：2096-1413(2017)14-0099-02

Clinical significance of serum procalcitonin and C-reactive protein levels in children with mycoplasma pneumonia
HUANG Ting, HAO Hai-yan, WANG Jing, RONG Qiang-quan, QUAN Yao


(Department of Pediatrics, Gaochun People`s Hospital, Nanjing 211300, China)

ABSTRACT: Objective To investigate the significance of serum procalcitonin (PCT) and C-reactive protein (CRP) levels in of children with mycoplasma pneumonia. Methods Fifty-six children with mycoplasma pneumonia were selected as the observation group, 54 children with bacterial pneumonia were selected as the control group A, 55 children with viral pneumonia were selected as the control group B and 50 healthy children were selected as the normal group; the observation group was divided into acute group (40 cases) and convalescent group (16 cases) according to the course of disease. The levels of serum PCT, CRP and positive rate 24 h after admission were detected and compared between the four groups were detected. The levels of serum PCT, CRP in the acute group and convalescent group were detected. Results The levels of serum CRP and PCT in the control group A, B and the observation group were significantly higher than those in the control group (P<0.05), the serum levels of CRP and PCT in the control group A were significantly higher than those in the observation group and the control group (P<0.05), the CRP level of the observation group was significantly higher than that of the control group B and the normal group (P<0.05). The positive rate of PCT and CRP in the control A group were significantly higher than those in control B group and observation group (P<0.05). the positive rates of PCT and CRP in the acute group and convalescent group were significantly higher than those in the normal group (P <0.05). Conclusion Combined detection of serum PCT and CRP in children with mycoplasma pneumonia may be useful for the differential diagnosis of bacterial pneumonia, and it can provide a valuable reference for clinical treatment.
KEYWORDS: mycoplasma pneumonia; serum procalcitonin; C-reactive protein

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