脑电双频指数及颅底静脉氧饱和度对急性脑损伤患者相关性及预后研究

张胜荣

（青田县人民医院重症医学科，浙江 丽水，197002）

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摘要：

目的 比较不同预后急性脑损伤患者的脑电双频指数（BIS）及颅底静脉氧饱和度（SjO₂），并探讨两种指标对急性脑损伤 的预后评估价值。方法 根据预后情况将40例急性脑损伤患者分为生存组（25例）和死亡组（15例），比较两组BIS、SaO₂、SjO₂ 及SaO₂ 和SjO₂ 的差值，并分析BIS、SjO₂与Glascow昏迷评分（GCS 评分）的相关性。结果 生存组BIS、SjO₂ 低于死亡组相应水平，Sa-jO₂ 高于死亡组水平，差异具有统计学意义（P<0.05）；SaO₂ 组间差异无统计学意义（P>0.05）。生存组GCS评分为（5.38±2.71）分，高于死亡组的（3.43±1.03）分，差异具有统计学意义（P<0.05）。生存组BIS值平均为（97.31±2.28）分、SjO₂ 平均为（67.51±4.27）分，经过Pearson相关性分析均与GCS评分呈正相关（r=0.401/0.389，P<0.05）。结论 BIS、SjO₂ 会随着急性脑损伤的严重程度而明显变化，能够客观地反映出疾病的预后。

关键词：脑电双频指数；颅底静脉氧饱和度；急性脑损伤；预后

中图分类号：R651文献标志码：A文章编号：2096-1413(2016)25-0012-02

The correlation and prognosis of cerebral electric double frequency index and cerebral venous oxygen saturation in patients with acute brain injury
ZHANG Sheng-rong
(Intensive Care Unit, Qingtian People`s Hospital, Lishui 197002, China)

ABSTRACT: Objective To compare the cerebral electrical double frequency index (BIS) and basal cerebral venous oxygen saturation (SjO₂) in patients with acute brain injury, and to explore the prognostic value of the two indexes in acute brain injury. Methods Forty patients with acute brain injury were divided to survival group (25 cases) and death group (15 cases) according to the prognosis condition BIS, SaO₂, SjO₂ and the difference between SaO₂ and SjO₂ in the two groups correlation between BIS, SjO₂ and Glascow Coma Scale (GCS score) were compared. Results The BIS, SjO₂ in the survival group were lower than those in the death group, and the SajO₂ was higher than that in the death group, the differences were statistically significant (P<0.05); there was no significant difference between SaO₂ in the two groups (P>0.05); the GCS score in the survival group was (5.38±2.71) points, which was higher than (3.43±1.03) points in the death group, the difference was statistically significant (P<0.05). In the surrival groups, the average value of BIS was (97.31±2.28) points,the average value of SjO₂ was (67.51 ±4.27) points, and they were positively correlated with GCS score after Pearson correlation analyzes (r=0.401/0.389, P<0.05). Conclusion SjO₂ and BIS can obviously change with the severity of acute brain injury, which can objectively reflect the prognosis of the disease.
KEYWORDS: cerebral electric double frequency index; oxygen saturation of the skull base; acute brain injury; prognosis

参考文献：
[1] 书国伟,张珏,费智敏,等.成人急性脑损伤脑电双频指数和格拉斯哥昏迷评分相关性研究[J].上海交通大学学报:医学版,2013,33(7):1010-1013.
[2] 王翠,王迪芬.脑电双频指数对判断急性脑损伤昏迷患者预后的价值[J].贵阳医学院学报,2015,40(7):727-729.
[3] 陈秀梅,雷燕妮,史中华,等.脑电双频指数预测脑损伤患者神经系统功能转归的应用[J].北京医学,2011,33(5):380-382.
[4] 牛世芹,袁俊亮,李海英,等.脑电双频指数在大面积脑梗死昏迷患者中的临床应用[J].中华老年心脑血管病杂志,2012,14(6):564-566.
[5] 蔡涛,徐子明,宋敏鹰,等.重型颅脑损伤脑灌注压及颈内静脉氧饱和度与预后的关系[J].国际医药卫生导报,2003,9(24):4-6.
[6] 汪晓波,王仁数,曲巍,等.脑电双频指数在脑复苏患者预后评估中的应用[J].实用医学杂志,2014,30(19):3121-3123.
[7] 黄昕,滕秀飞,杨延超,等.低血红蛋白对全麻患者脑氧饱和度及术后认知功能的影响[J].中国医科大学学报,2016,45(1):35-38.
[8] 张明,钱俊英,徐拥庆,等.脑电双频指数在评估心肺复苏术后患者脑功能及预后中的价值[J].中华急诊医学杂志,2015,24(1):38-42.
[9] 杨胜,张冬惠,王绍谦,等.NSE 与BIS 监测在评估重度一氧化碳中毒患者脑功能及预后中的临床应用[J].东南大学学报:医学版,2016,35(1):92-97.