丹红注射液联合泮托拉唑治疗呼吸衰竭急性加重期的疗效观察

杨建章，郭海瑶

（泾阳县中医医院内科，陕西 咸阳，713700）

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摘要：

目的 探讨丹红注射液联合泮托拉唑治疗呼吸衰竭急性加重期的临床疗效。方法 选取我院收治的110例呼吸衰竭急性加重期患者为研究对象，根据随机数字表法分为研究组及对照组，每组55例。对照组患者采用常规支持治疗，研究组在其基础上采用丹红注射液联合泮托拉唑进行治疗，对比两组患者的临床治疗效果。结果 研究组显效35例（63.64%），有效17例（30.91%），无效3例（5.45%），治疗总有效率为94.55%（52/55）；对照组显效20例（36.36%），有效21例（38.18%），无效14例（25.45%），治疗总有效率为74.55%（41/55），研究组治疗总有效率高于对照组，差异有统计学意义（P<0.05）。治疗前两组患者的血浆黏度、血浆乳酸、PaO₂、PaCO₂ 以及SaO₂ 比较无显著性差异（P>0.05），治疗后研究组血浆黏度、血浆乳酸、PaO₂、PaCO₂以及SaO₂ 显著优于对照组（P<0.05）。结论呼吸衰竭急性加重期患者采用丹红注射液联合泮托拉唑进行治疗，能有效改善患者的临床症状，提高治疗效果，值得临床推广应用。

关键词：丹红注射液；泮托拉唑；呼吸衰竭；急性加重期

中图分类号：R563.8文献标志码：A文章编号：2096-1413(2016)26-0004-02

Effect observation of Danhong injection combined with pantoprazole in the treatment of acute exacerbation of respiratory failure
YANG Jian-zhang, GUO Hai-yao
(Department of Internal Medicine, Traditional Chinese Medicine Hospital in Jingyang County,


Xianyang 713700, China)

ABSTRACT: Objective To investigate the clinical efficacy of Danhong injection combined with pantoprazole in the treatment of acute exacerbation of respiratory failure. Methods One hundred and ten patients with acute exacerbation of respiratory failure admitted in our hospital were selected as the research objects and divided into research group and control group according to the random number table method, with 55 patients in each group. The control group was treated with routine supportive treatment, while the research group was given Danhong injection combined with pantoprazole treatment based on the control group. Then the clinical curative effect was compared between the two groups. Results In the research group, 35 cases (63.64%) were markedly effective, 17 cases (30.91%) were effective, 3 cases (5.45%) were ineffective, the total effective rate was 94.55% (52/55). In the control group, 20 cases (36.36%) were markedly effective, 21 cases (38.18%) were effective, 14 cases (25.45%) were ineffective, the total effective rate was 74.55% (41/55). The total effective rate of the research group was higher than that of the control group, the difference was statistically significant (P<0.05). The plasma viscosity, plasma lactic acid, PaO₂, PaCO₂ and SaO₂ in the two groups has no significant difference before treatment; the plasma viscosity, plasma lactic acid, PaO₂, PaCO₂ and SaO₂ in the research group were significantly better than those in the control group after treatment (P<0.05). Conclusion Danhong injection combined with pantoprazole has good effect on patients with acute exacerbation of respiratory failure, which can effectively improve the patients` clinical symptoms and the therapeutic effect. It is worthy of clinical application.
KEYWORDS: Danhong injection; pantoprazole; respiratory failure; acute exacerbation

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