中国学术期刊网络出版总库入编期刊
CNKI中文期刊全文数据库全文收录期刊
中国核心期刊(遴选)数据库全文收录期刊
万方数据——数字化期刊群收录期刊
中文科技期刊数据库全文收录期刊

主管:陕西省卫生健康委员会
主办:西安心身医学研究所
   西安交通大学第一附属医院
国际标准刊号:ISSN2096—1413
国内统一刊号:CN61—1503/R

内镜黏膜下切除术治疗消化道肿瘤性病变的临床分析

王亚军,王让兰

(陕西省宝鸡市岐山县医院消化内科,陕西 宝鸡,722400)

浏览次数:88次 下载次数:366次

摘要:

目的 分析内镜黏膜下切除术(EMR)治疗消化道肿瘤性病变的临床疗效。方法 选取我院应用内镜下黏膜切除术进行 病变切除治疗的62 例消化道肿瘤性病变患者作为研究对象,分析患者术后疗效及并发症发生情况。结果 108个病灶均完全切除,治疗成功率为100%,其中105个病灶均为一次性切除,所切除病灶范围为0.4 ~6.0 cm。并发症分析:术中创面少量出血6例,直肠早期腺癌术后迟发出血1 例,经及时处理后均有效止血;术后无管腔狭窄、穿孔、局限性腹膜炎等严重并发症。镜下观察:32个病灶形态为宽基息肉,25个病灶形态为有蒂息肉,16个病灶形态为亚蒂息肉,10个病灶形态为结节样息肉样隆起,8个病灶形态结节样息肉样隆起,5个病灶形态半圆形/类圆形膜隆起,11个扁平型病变,1个侧向发育型肿瘤。随访1年,完全切除病灶者复查原切除部位未见病变残留或复发。结论 内镜下黏膜切除术是一种安全微创的内镜治疗手段,可以 有效、完整切除消化道肿瘤病变,并发症少,安全性好,值得临床推广。

关键词:消化道肿瘤性病变;内镜下黏膜切除术;并发症

中图分类号:R735文献标志码:A文章编号:2096-1413(2016)27-0093-02

    Clinical analysis of endoscopic mucosal resection for gastrointestinal cancer lesions
    WANG Ya-jun, WANG Rang-lan
    (Department of Gastroenterology, Qishan County Hospital, Baoji 722400, China)

    ABSTRACT: Objective To analyze the clinical effect of endoscopic mucosal resection (EMR) for gastrointestinal cancer lesions. Methods Sixty -two patients with gastrointestinal cancer lesions in our hospital were treated with endoscopic mucosal resection and selected as study objects. The clinical curative effect and complications of the patients after the operation were analyzed. Results One hundred and eight lesions were completely removed, the success rate of the treatment was 100%, in which 105 lesions were removed at the first surgery, the range of the excised lesions were 0.4-6.0 cm. The analysis of complications: there were 6 cases with a little intraoperative bleeding at the surface of the wound, 1 case with rectal adenocarcinoma early postoperative delayed bleeding, all the patients were treated with effective hemostasis in time. After the operation, there were no serious complications such as stenosis, perforation, localized peritonitis, etc. the endoscopic observation showed that the shape of 32 lesions was wide polyps, the shape of 25 lesions was pedunculated polyp morphology, the shape of 16 lesions was rebagliati polyps, the shape of 10 lesions was nodular polypoid bulge, the shape of 8 lesions was nodular polypoid bulge, the shape of 5 lesions was semi-circular/oval film bulge, the shape of 11 lesions were flat, 1 case was lateral developmental tumors. After one year followed up, the patients who had complete resection of the lesion had no residual or recurrence. Conclusion Endoscopic mucosa resection is a safe minimally invasive therapy, which can remove the digestive tract tumor lesions effectively with less complications, it has better security and is worthy of being widely applied in clinic.
    KEYWORDS: gastrointestinal cancer lesions; endoscopic mucosal resection; complications

    参考文献:
    [1] 何运花.全程健康教育模式在糖尿病护理管理中的应用分析[J].中国卫生标准管理,2016,16(2):204-205.
    [2] 唐闯.内镜下黏膜切除术在早期消化道肿瘤中的临床应用[J].中国医药指南,2012,10(20):18-19.
    [3] 朱晓蕾,陈志坦.消化道无蒂隆起性病变的内镜黏膜切除术和内镜黏膜下剥离术治疗分析[J].实用临床医药杂志,2012,16(24):40-42.
    [4] 刘莹.内镜经黏膜下隧道肿瘤切除术治疗上消化道黏膜下肿瘤的探讨[D].济南:山东大学,2014.
    [5] 林立.内镜下黏膜切除术治疗消化道平坦性病变的临床观察[J].临床医药文献电子杂志,2014,17(7):336.
    [6] 王亚楠,李艳梅,卢雪峰.内镜经黏膜下隧道肿瘤切除术治疗上消化道固有肌层肿瘤的临床价值[J].世界华人消化杂志,2015,23(5):793-799.
    [7] 杨莉,李胜昔,徐美东,等.内镜黏膜下剥离术及全层切除术治疗胃黏膜下肿瘤的临床疗效分析[J].中国内镜杂志,2015,21(1):37-41.
    [8] 李龙飞,马宏珍,张哲华,等.94 例下消化道肿瘤内镜下黏膜切除术的临床分析[J].内蒙古民族大学学报:自然科学版,2015,30(1):77-79.
    [9] 奚肇宏,田耀洲,梅军,等.内镜黏膜下剥离术治疗上消化道肿瘤性病变疗效分析[J].中华全科医学,2015,13(4):679-680.
    [10] 张其胜,徐建华,高鹏,等.内镜下黏膜切除术或剥离术治疗结肠表浅肿瘤性病变并发电凝综合征临床表现及危险因素分析[J].胃肠病 学和肝病学杂志,2015,24(7):799-801.
    [11] 阮国永,梁爱霞,邱桂梅,等.注射法内镜下黏膜切除术及透明帽辅助法内镜下黏膜切除术治疗大肠无蒂肿瘤性病变的临床观察[J].实 用医学杂志,2011,27(2):215-217.
    [12] 李晓波,陈慧敏,高云杰,等.结直肠肿瘤样病变内镜活检与黏膜切除术后病理诊断比较[J].胃肠病学,2009,14(10):604-606.
    [13] 欧锦溪,朱志华,谢玉丽.内镜黏膜切除术治疗消化道隆起性病变的临床价值[J].中外医学研究,2013,11(24):187-188.
    [14] 傅林海,陈天翔,胡坚.内镜黏膜下隧道切除术治疗上消化道肿瘤疗效分析[J].中华胸部外科电子杂志,2015,2(4):259-265.
    [15] 张莹,文琴,何向阳.内镜下黏膜切除术治疗消化道黏膜隆起性病变疗效分析[J].安徽医学,2013,34(10):1492-1493.
    [16] 凌安生,朱芳来,余琳芳.内镜黏膜下剥离治疗消化道肿瘤性病变临床观察[J].中国内镜杂志,2011,17(2):197-198.

上一篇头孢呋辛钠与清开灵联用治疗老年肺气肿合并感染临床分析

下一篇改良式腹直肌外缘切口手术治疗阑尾炎的临床疗效