不同孕期和年龄孕妇甲状腺功能指标的比较分析

杜云旺1 ，马玲2

（1.镇安县妇幼保建院检验科，陕西 商洛，711500；2.镇安县医院检验科，陕西 商洛，711500）

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摘要：

目的 分析不同孕期和年龄孕妇甲状腺功能指标的变化情况。方法 收集2014年1月至2016年12月于我院进行孕期常规检查的孕妇149例，根据孕期分为孕早期组、孕中期组和孕晚期组，根据年龄分为20～27 岁组、28～34 岁组和35～43岁组。收集同期我院健康体检非妊娠女性50 人为对照组，比较不同孕期、年龄被检者的血清FT3、FT4、TSH、T3、T4 水平。结果不同孕产期孕妇血清FT3、FT4 水平低于对照组，T3、T4、TSH水平高于对照组（P<0.05）。随着孕期的延长，孕妇血清FT3、 FT4水平逐渐降低，T3、T4、TSH水平逐渐升高，孕早期的FT3、FT4水平高于孕中、晚期及孕晚期的TSH 水平高于孕早、中期（P<0.05）。随着孕妇年龄增加，血清FT3、FT4、TSH、T3、T4 水平逐渐降低。20～27岁组和35～43 岁组孕妇血清FT4、T4、TSH 水平有明显差异（P<0.05）；28～34组和35～43 岁组孕妇血清FT4、T4 水平有明显差异（P<0.05）。结论 不同孕期和年龄的孕妇甲状腺功能指标存在差异，应加强孕期甲状腺功能监测。

关键词：孕期；年龄；甲状腺功能

中图分类号：R581文献标志码：A文章编号：2096-1413(2017)20-0045-02

Comparative analysis of thyroid function indexes in pregnant women of different pregnancy and age
DU Yun-wang 1, MA Ling 2
(1. Department of Laboratory Medicine, Zhen``an Maternal and Child Health Hospital, Shangluo 711500; 2. Department of Laboratory Medicine, Zhen``an County Hospital, Shangluo 711500, China)

ABSTRACT: Objective To explore the changes of thyroid function indexes in pregnant woman of different pregnancy and age. Methods From January 2014 to December 2016, 149 pregnant women in our hospital were selected and divided into early pregnancy group, middle pregnancy group and late pregnancy group on the basis of pregnancy and 20-27 age group, 28-34 age group and 35-43 age group on the basis of age, other 50 non-pregnant women in the same period were selected as the control group. The levels of serums FT3, FT4, TSH, T3, T4 in different pregnancy and age were compared. Results The levels of serum FT3 and FT4 in pregnant women were lower than those in the control group, and the levels of T3, T4 and TSH were higher than those in the control group (P<0.05). With the prolongation of pregnancy of pregnant women, the serum FT3, FT4 levels gradually decreased, while T3, T4, TSH levels gradually increased, the FT3, FT4 levels in the early pregnancy were higher than those of the middle and late pregnancy, the TSH level in the late pregnancy was higher than that of the middle and late pregnancy (P<0.05). With the increase of age of pregnant women, the serum FT3, FT4, TSH, T3, T4 levels gradually decreased, there were significant differences in serum FT4, T4 and TSH levels between the 20-27 age group and 35-43 age group (P<0.05); there were significant differences in serum FT4 and T4 levels between the 28-34 age group and 35-43 age group (P<0.05). Conclusion There are differences in the thyroid function indexes in pregnant woman with difference pregnancy and age, and intensive monitoring of thyroid function markers should be taken in pregnancy.
KEYWORDS: pregnancy; age; thyroid function

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