百乐眠胶囊联合右佐匹克隆片治疗失眠40例效果观察

李玲1，王凌1 ，王莉2

（1.陕西省中医医院老年病科，陕西 西安，710003；2.陕西省人民医院神经内科，陕西 西安，710004）

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摘要：

目的 观察和比较百乐眠胶囊联合右佐匹克隆片与单用右佐匹克隆片治疗失眠的临床疗效。方法 选取2013年11月至2015年7月陕西省中医医院收治的80 例失眠患者，随机分为治疗组和对照组，各40例。治疗组采用百乐眠胶囊联合右佐匹克隆片，对照组单用右佐匹克隆片，两组均治疗15 d。比较两组患者的临床疗效和不良反应发生率。结果 治疗第7天和第15 天，两组SDRS评分均显著降低，且治疗组SDRS评分显著低于对照组，差异有统计学意义（P<0.05）；治疗组治疗前、后的减分差显著大于对照组，差异有统计学意义（P<0.05）；治疗第15天，治疗组有效率为80.0%，明显高于对照组的55.0%，差异有统计学意义（P<0.05）。治疗组口干、便秘、腹泻、头晕及乏力等不良反应发生率明显低于对照组，差异有统计学意义（P<0.01）。结论 百乐眠胶囊联合右佐匹克隆片治疗失眠症疗效显著，且疗效优于单用右佐匹克隆片，其不良反应轻。

关键词：失眠；百乐眠胶囊；中西医结合治疗

中图分类号：R740文献标志码：A文章编号：2096-1413(2017)20-0096-02

Effect observation on 40 cases of insomnia treated by Bailemian capsules combined with eszopiclone tablets
LI Ling 1, WANG Ling 1, WANG Li 2
(1. Department of Geriatrics, Shaanxi Provincial TCM Hospital, Xi``an 710003; 2. Department of Neurology, Shaanxi Provincial

People``s Hospital, Xi``an 710004, China)

ABSTRACT: Objective To observe and compare the effect on 40 cases of insomnia treated by Bailemian capsules combined with eszopiclone tablets. Methods Eighty patients with insomnia in Shaanxi Provincial TCM Hospital from November 2013 to July 2015 were selected and randomly divided into treatment group and control group, with 40 cases in each goups. The treatment group was treated with Bailemian capsule combined with eszopiclone tablets, while the control group was treated with single eszopiclone tablets, and both groups were treated for 15 days. Then the clinical efficacy and the incidence of adverse reactions were compared between the two groups. Results On the 7th day and the 15th day after treatment, the SDRS scores of the two groups were significantly decreased, and the SDRS scores in the treatment group were significantly lower than those in the control group (P<0.05); the deduction difference in the treatment group before and after treatment were significantly bigger than that in the control group (P<0.05). On the 15th day after treatment, the effective rate was 80.0% in the treatment group, which was significantly higher than 55.0% in the control group (P<0.05). The incidence of adverse reactions such as dry mouth, constipation, diarrhea and fatigue in the treatment group was significantly lower than that in the control group (P<0.01). Conclusion Bailemian capsules combined with eszopiclone tablets has remarkable curative effect in the treatment of insomnia, and the curative effect is better than that of single eszopiclone tablets, with light adverse reactions.
KEYWORDS: insomnia; Bailemian capsule; traditional Chinese and western medicine

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