柴胡白芍汤灌肠治疗溃疡性结肠炎的临床观察

杜延

（西安医学院附属宝鸡医院，陕西 宝鸡，721006）

浏览次数：120次 下载次数：385次

摘要：

目的 探讨柴胡白芍汤灌肠治疗溃疡性结肠炎的临床效果。方法 选取2013年1月至2016年1月我院收治的200例溃疡性结肠炎患者为研究对象，随机分为对照组和研究组，每组100 例。两组患者均给予对症综合治疗，对照组口服柳氮磺胺吡啶片；研究组在对照组的基础上，用柴胡白芍汤灌肠。比较两组患者治疗后临床疗效、症状及体征缓解情况、结肠镜检查结果。结果 研究组患者的总有效率，粘液脓血便、腹痛、腹泻等症状的治疗缓解率及充血水肿、糜烂和溃疡的缓解率均高于对照组，差异均有统计学意义（P<0.05）。结论 用柴胡白芍汤治疗溃疡性结肠炎可显著地提高疗效，降低复发率，而且药物价格低廉，易于操作，未见明显不良反应，值得在临床上推广应用。

关键词：柴胡白芍汤；溃疡性结肠炎；柳氮磺胺吡啶片

中图分类号：R574.1 文献标志码：A文章编号：2096-1413(2017)20-0106-02

Clinical observation of enema with bupleurum and raeoniae decoction in treatment of ulcerative colitis
DU Yan
(the Affiliated Baoji Hospital of Xi``an Medical College, Baoji 721006, China)

ABSTRACT: Objective To investigate the clinical effect of enema with bupleurum and raeoniae decoction in treatment of ulcerative colitis. Methods Two hundred cases of patients with ulcerative colitis in our hospital from January 2013 to January 2016 were selected as the study objects, all the patients were randomly divided into study group and control group, with 100 cases in each group. Two groups of patients were given symptomatic treatment, the control group was treated with sulfasalazine, on this basis, the study group were clystered with bupleurum and raeoniae decoction. The remission of clinical symptoms and signs after treatment were compared between the two group. Results The total effective rates, treatment improvement rates of patients with mucopurulent stool, abdominal pain, diarrhea and other symptoms, remission rstes of mucosal hyperemia, edema, erosion, ulcerations in the study group were significantly higher than those in the control group (P<0.05). Conclusion Bupleurum and raeoniae decoction can effectively improve the efficacy and reduce recurrence of ulcerative colitis, with lower price and no obvious adverse reactions, which is worthy of clinical application.

KEYWORDS: bupleurum and raeoniae decoction; ulcerative colitis; sulfasalazine

参考文献：
[1] 方欣.柴胡白芍甘草汤治疗消化性溃疡58 例疗效观察[J].安徽预防医学杂志,2007,13(4):318.
[2] 勾春宏.康复新液保留灌肠治疗溃疡性结肠炎的临床研究[J].中医临床研究,2010,2(10):1-2.
[3] 刘仕兰.柴胡白芍汤灌肠治疗溃疡性结肠炎的临床观察[J].临床医学工程,2009,16(5):62-63.
[4] 李国峰.康复新保留灌肠治疗轻中度远端溃疡性结肠炎25 例疗效观察[J].中国实用医药,2009,4(24):152.
[5] 中华医学会消化病学分会.对炎症性肠病诊断治疗规范的建议[J].中华消化杂志,2001,21(4):236-239.
[6] 中华医学会消化病学分会炎症性肠病协作组. 对我国炎症性肠病诊断治疗规范的共识意见[J].现代消化及介入诊疗,2008,13(2):139-145.


[7] 张禄芳,翁世美.中西医结合治疗慢性溃疡性结肠炎84 例疗效观察[J].新中医,2003,35(6):48-49.
[8] 吕文,张筱凤,张啸.康复新液保留灌肠治疗溃疡性结肠炎临床疗效观察[J].中国综合临床,2003,19(10):912-913.
[9] 刘立全.中药灌肠治疗溃疡性结肠炎的研究近况[J].医药产业资讯,2005.26(8):88-89.