雾化吸入布地奈德治疗小儿哮喘急性发作的效果观察

张芬

（户县妇幼保健院儿内科，陕西 西安，710300）

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摘要：

目的 探讨雾化吸入布地奈德治疗小儿哮喘急性发作的临床效果。方法 将我科室2013年至2015年收治的100例哮喘急性发作患儿随机分为对照组与观察组，每组50例患儿。对照组患儿入院后接受常规解痉平喘、抗感染、祛痰、纠正酸碱平衡紊乱等对症治疗措施，观察组患儿在此基础上给予布地奈德雾化吸入治疗措施，观察对比两组哮喘急性发作患儿的临床疗效以及咳嗽、喘息、肺部哮鸣音等症状体征的消失时间和住院时间。结果 治疗3 d 后，观察组患儿的临床治疗总有效率明显高于对照组（96.00% vs. 84.00%），差异有统计学意义（P<0.05）；观察组患儿咳嗽、喘息、肺部哮鸣音等症状体征的消失时间均短于对照组（P<0.05）；观察组患儿平均住院时间短于对照组（P<0.05）。结论 在常规对症治疗的基础上联合雾化吸入布地奈德治疗，可明显提高小儿哮喘急性发作的治疗效果，促进患儿康复，值得临床推广应用。

关键词：雾化吸入；布地奈德；小儿哮喘；急性发作期

中图分类号：R725.6文献标志码：A文章编号：2096-1413(2017)22-0105-02

Effect observation of budesonide atomization inhalation in the treatment of children with asthma acute attack
ZHANG Fen
(Department of Pediatrics Medicine, Maternal and Child Health Care of Hu County, Xi``an 710300, China)

ABSTRACT: Objective To explore the clinical effect of budesonide atomization inhalation in the treatment of children with asthma acute attack. Methods One hundred cases of children with asthma acute attack admitted in our department from 2013 to 2015 were selected and randomly divided into control group and observation group, with 50 cases in each group. The cases in the control group took conventional antispasmodic asthma, anti-infection, expectorant, correct acid-base balance disorder and other symptomatic treatment, and the cases in the observation group were given budesonide atomization inhalation on the basis of the control group. The clinical effect and the extinction time of cough, dyspnea and sibilant, as well as hospital stay between the two groups were compared. Results After 3 days treatment, the total effective rate in the observation group was higher than that in the control group (96.00% vs. 84.00%), the difference was statistically significant (P<0.05). The extinction time of cough, dyspnea and sibilant in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05). The average hospitalization time in the observation group was shorter than that in the control group (P<0.05). Conclusion Budesonide atomization inhalation in the treatment of children with asthma acute attack can improve the clinical effect and promote speedy recovery of the children patients, which is worthy of clinic application.
KEYWORDS: atomization inhalation; budesonide; infantile asthma; acute attack

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