排石颗粒联合盐酸坦索罗辛对体外震波碎石后输尿管中下段结石的疗效观察

杨冰，周哲，潘东亮，晋连超，何赛男，李宁忱

（北京大学首钢医院泌尿外科，北京，100144）

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摘要：

目的 研究输尿管中下段结石体外震波碎石（ESWL）后应用排石颗粒联合盐酸坦索罗辛的治疗效果。方法 选取我院输尿管中下段结石患者100例，随机分为观察组和对照组，各50例。两组患者均行ESWL治疗，在此基础上，观察组口服排石颗粒及盐酸坦索罗辛，对照组口服坦排石颗粒。比较两组患者治疗后的临床效果。结果 观察组患者体外碎石治疗后7、14 和 21 d的结石清除率分别为58.0%、66.0%和88.0%，明显高于对照组的44.0%、58.0%和74.0%（P<0.05）。观察组行二次ESWL率为32.0%，明显低于对照组的44.0%；观察组治疗后总有效率为92.0%，明显高于对照组的80.0%；观察组肾绞痛发生率为 20.0%，明显低于对照组的30.0%，差异均有统计学意义（P<0.05）。结论 排石颗粒与坦索罗辛联用能有效促进ESWL 后患者输尿管中下段结石的结石排出，疗效显著。

关键词：输尿管结石；排石颗粒；盐酸坦索罗辛；体外震波碎石

中图分类号：R693.4 文献标志码：A文章编号：2096-1413(2017)24-0124-02

Effect of lithagogue powder combined with tamsulosin hydrochloride on patients with middle-lower ureteral calculus after extracorporeal shock wave lithotripsy
YANG Bing, ZHOU Zhe, PAN Dong-liang, JIN Lian-chao, HE Sai-nan, LI Ning-chen


(Urology Surgery, Shougang Hospital of Peking University, Beijing 100144, China)

ABSTRACT: Objective To study the effect of lithagogue powder combined with tamsulosin hydrochloride on patients with middle -lower ureteral calculus after extracorporeal shock wave lithotripsy (ESWL). Methods A total of 100 cases of patients with middle -lower ureteral calculus in our hospital were randomly divided into observation group and control group, with 50 cases in each group. Both the two groups were treated with ESWL. On this basis, the observation group received lithagogue powder combined with tamsulosin hydrochloride, while the control group received oral lithagogue powder. The effects of the treatment of the two groups were compared. Results The removal rate of stone were 58.0% , 66.0% and 88.0% at 7, 14 and 21 days after the treatment of the ESWL in the observation group, which were significantly higher than 44.0%, 58.0% and 74.0% in the control group (P<0.05). The secondary ESWL rate of the observation group was 32.0%, which was significantly lower than 44.0% of the control group; the total effective rate was 92.0% in the observation group, which was significantly higher than 80.0% in the control group; the incidence of renal colic in the observation group was 20.0%, which was significantly lower than 30.0% in the control group, the differences were statistically significant (P<0.05). Conclusion Lithagogue powder and tamsulosin hydrochloride can effectively promote the exclusion of stones for patients with middle-lower ureteral calculus after extracorporeal shock wave lithotripsy, and the effect is significant.

KEYWORDS: ureteral stone; lithagogue powder; tamsulosin hydrochloride; extracorporeal shock wave lithotripsy (ESWL)

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