奥曲肽联合立止血治疗急性上消化道出血的临床疗效分析

张高峰

（柞水县医院，陕西 商洛，711400）

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摘要：

目的 分析奥曲肽联合立止血治疗急性上消化道出血的临床疗效。方法 选择我院2014年6月至2016年6月收治的80例急性上消化道出血的患者作为本次研究对象，按照随机数字表法分为对照组和观察组，对照组采用奥曲肽治疗，观察组在奥曲肽治疗的基础上联合使用立止血，比较两组的临床治疗效果。结果 对照组与观察组的治疗总有效率分别为75.00%、92.50%，观察组的治疗总有效率明显优于对照组（P<0.05）；观察组平均止血时间为（24.23±2.34）min，明显低于对照组的（44.68±3.18） min，差异具有统计学意义（P<0.05）；两组均未发生严重不良反应。结论 奥曲肽联合立止血治疗急性上消化道出血疗效显著， 能在短时间内控制患者的出血，减少出血量，此方法可在临床推广使用。

关键词：奥曲肽；立止血；急性上消化道出血

中图分类号：R573文献标志码：A文章编号：2096-1413(2017)28-0015-02

Clinical effect analysis of octreotide combined with reptilase in the treatment of acute upper gastrointestinal hemorrhage
ZHANG Gao-feng
（Zhashui County Hospital, Shangluo 711400, China）

ABSTRACT: Objective To analyze the clinical curative effect of octreotide combined with reptilase in the treatment of acute upper gastrointestinal hemorrhage. Methods A total of 80 patients with acute upper gastrointestinal hemorrhage admitted in our hospital from June 2014 to June 2016 were selected as the subjects of this study. Patients were divided into control group and observation group according to random number table method, the control group was treated with octreotide, the observation group was given reptilase on the basis of octreotide. The clinical effects of the two groups were compared. Results The total effective rate of the control group and the observation group were 75.00% and 92.50% respectively, and the total effective rate of the observation group was better than that of the control group （P<0.05）. The average hemostasis time of the observation group was （24.23 ±2.34）min, which was significantly lower than that of the control group（44.68±3.18）min, the difference was statistically significant （P<0.05）. No serious adverse reactions occurred in the two groups. Conclusion Octreotide combined with reptilase in the treatment of acute upper gastrointestinal hemorrhage has remarkable curative effect, which could control the bleeding of patients in a short period of time, reduce the amount of bleeding, this method can be used in clinical practice.
KEYWORDS: octreotide; reptilase; acute upper gastrointestinal hemorrhage

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