慢阻肺患者采用无创呼吸机治疗对其呼吸症状及生活质量的影响分析

朱文忠1，韩亚利1 ，魏子妤2

（1.宝鸡市金台医院，陕西 宝鸡，721000；2.苏州大学，江苏 苏州，215123）

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摘要：

目的 研究慢阻肺患者采用无创呼吸机治疗对其呼吸症状及生活质量的影响。方法 选择2013年1月至2015年12月在我院进行诊治的慢阻肺患者200例，随机分为对照组和研究组，每组100例。对照组进行常规治疗，观察组采用无创呼吸机进行治疗，比较两组患者的临床治疗效果，生活质量评分及心率、呼吸频率、pH、氧分压和二氧化碳分压等血气分析结果。结果 观察组患者的治疗总有效率为96.00%，明显高于对照组的82.00%（P<0.05）。观察组患者的躯体功能、情绪功能、角色 功能和社会功能评分均明显高于对照组（P<0.05）。观察组患者的心率和呼吸频率均明显优于对照组（P<0.05），但两组患者 的pH、氧分压和二氧化碳分压比较，无显著差异（P>0.05）。结论 慢阻肺患者采用无创呼吸机治疗可以有效改善其呼吸症状和生活质量，具有较好的治疗效果。

关键词：慢阻肺；无创呼吸机；呼吸症状；生活质量

中图分类号：R563.8文献标志码：A文章编号：2096-1413(2017)32-0022-02

Effect of non-invasive ventilator therapy on the respiratory symptoms and quality of life in patients with chronic obstructive pulmonary disease
ZHU Wen-zhong 1, HAN Ya-li 1, WEI Zi-yu 2
(1. Jintai Hospital of Baoji, Baoji 721000; 2. Soochow University, Suzhou 215123, China）

ABSTRACT: Objective To study the influence of non-invasive ventilator therapy on the respiratory symptoms and quality of life in patients with chronic obstructive pulmonary disease (COPD). Methods From January 2013 to December 2015, 200 patients with COPD in our hospital were selected and randomly divided into control group and observation group, with 100 cases in each group. The control group was treated with routine treatment, and the observation group was treated with non-invasive ventilation therapy. The clinical effects, quality of life scores, blood gas analysis results such as heart rate, respiratory rate, pH, oxygen partial pressure and carbon dioxide partial pressure between the two groups were compared. Results The total effective rate in the observation group was 96.00%, which was significantly higher than 82.00% of the control group (P<0.05). The body function, emotional function, role function and social function scores of the observation group were significantly higher than those of the control group (P<0.05). The heart rate and respiratory rate of the observation group were significantly better than those of the control group (P <0.05), but there were no significant differences in the pH, oxygen partial pressure and carbon dioxide partial pressure between the two groups (P>0.05). Conclusion Non -invasive ventilation therapy can effectively improve the respiratory symptoms and quality of life in patients with COPD, which has good clinical treatment effect.
KEYWORDS: chronic obstructive pulmonary disease (COPD); non-invasive ventilator; respiratory symptoms; quality of life

参考文献：
[1] 赵云峰,姜艳平,程改存,等.圣乔治呼吸问卷和慢性阻塞性肺疾病评估测试问卷评价慢性阻塞性肺疾病稳定期患者健康相关生活质 量的比较[J].上海医学,2013,36(1):47-51.
[2] 龙瑜琴,程晓明.噻托溴铵联合大剂量舒利迭治疗重度支气管哮喘合并慢性阻塞性肺疾病的效果观察[J].中国医药导报,2013,10(2):166-168.
[3] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南(2007 年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17.
[4] 钟南山.早发现、早诊断和早干预应是我国慢性阻塞性肺疾病防治的主要研究方向[J].中华结核和呼吸杂志,2012,35(4):243-245.
[5] 李建生,李彬,余学庆,等.活血化瘀方药治疗血瘀证慢性阻塞性肺疾病急性加重期的临床疗效评价[J].中国中西医结合急救杂志,2011,18(1):9-13.
[6] 孙治霞,申亚晖,韩丽华,等.有创机械通气不同实施时机对慢性阻塞性肺疾病急性发作合并重度呼吸衰竭患者治疗疗效的影响研究 [J].中国全科医学,2012,15(7):767-768.
[7] 刘伟,黄晓日,刘丰梅,等.沙美特罗/氟替卡松对慢性阻塞性肺疾病 患者急性加重期气道炎症的影响[J].中国基层医药,2011,18(12):1616-1618.
[8] 谭伟,孙龙凤,代冰,等.慢性阻塞性肺疾病急性加重合并域型呼吸 衰竭患者使用无创正压通气成功的临床预测因素研究[J].中国全科 医学,2013,16(1B):147-150.