尿糖与尿微量白蛋白联合检验诊断糖尿病早期肾损伤的应用价值

吕文艳1 ，白雅红2

（1.西安医学院附属宝鸡医院医学检验科，陕西 西安，721006；2.宝鸡市人民医院检验科，陕西 宝鸡，721000）

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摘要：

目的 探讨尿糖与尿微量白蛋白联合检验诊断糖尿病早期肾损伤的临床价值。方法 随机选择我院收治的160 例糖尿 病患者，其中80 例肾病合并糖尿病患者为研究组，其他80 例无肾病患者为对照组，再抽取同期门诊体检的80 例健康人群 为空白组，比较3 组尿糖与尿微量白蛋白水平。结果 研究组尿糖为（3.71±1.20）mmoL/L，尿微量白蛋白为（26.60±10.08）mg/L；对 照组尿糖为（2.01±0.49）mmoL/L，尿微量白蛋白为（27.10±11.25）mg/L；空白组尿糖为（2.22±0.53）mmoL/L，尿微量白蛋白 为（16.03±7.49）mg/L。研究组尿糖水平明显高于对照组和空白组，尿微量白蛋白水平明显高于空白组（P<0.05）；对照组 尿微量白蛋白水平明显高于空白组（P<0.05）。研究组尿糖阳性率81.25%，尿微量白蛋白阳性率51.25%；对照组尿糖阳 性率0.00%，尿微量白蛋白阳性率52.50%；空白组尿糖阳性率0.00%，尿微量白蛋白阳性率0.00%。研究组尿糖与尿微量 白蛋白阳性率均高于空白组，差异有统计学意义（P<0.05）。结论 糖尿病早期肾损伤应用尿糖与尿微量白蛋白联合检验具有 重要的诊断价值，值得临床推广应用。

关键词：糖尿病；肾损伤；尿糖；尿微量白蛋白

中图分类号：R587.2文献标志码：A文章编号：2096-1413(2017)34-0039-02

Application value of urine glucose combined with urine microalbumin detection in early diabetic nephropathy
LV Wen-yan 1, BAI Ya-hong 2
(1. Medical Laboratory Department, Baoji Hospital, the Affiliated Hospital of Xi``an Medical University, Xi``an 721006; 2. Laboratory Department,

Baoji People``s Hospital, Baoji 721000, China)

ABSTRACT: Objective To discuss the clinical value of urine glucose combined with urine microalbumin detection in early diabetic with urine glucose. Methods One hundred and sixty diabetic patients in our hospital were randomly selected as the study objects, 80 patients with nephropathy complicated with diabetes were included in the study group, the other 80 patients without nephropathy were included in the control group, and 80 healthy people underwent outpatient physical examination were selected as the blank group at the same period. The levels of urinary glucose and urine microalbumin were compared in the three groups. Results The levels of urine glucose and microalbumin in the study group were (3.71±1.20) mmoL/L, (26.60±10.08) mg/L; the levels of urine glucose and microalbumin in the control group were (2.01±0.49) mmoL/L, (27.10±11.25) mg/L; the levels of urine glucose and microalbumin in the blank group were (2.22±0.53) mmoL/L, (16.03±7.49) mg/L. The level of urinary glucose in the study group was significantly higher than that of the control group and blank group, the level of microalbumin in the study group was significantly higher than that in the blank group (P<0.05); the level of microalbumin in the control group was significantly higher than that in the blank group (P<0.05). The positive rate of urinary glucose and microalbumin in the study group were 81.25%, 51.25%; the positive rate of urinary glucose and microalbumin in the control group were 0.00%, 52.50%; the positive rate of urinary glucose and microalbumin in the blank group were 0.00%, 0.00%; the positive rate of urine glucose and microalbumin in the study were higher than those in the blank group, the differences were statistically significant (P<0.05). Conclusion The combination of urine glucose and microalbumin in early diabetic with renal injury has important diagnostic value, which is worthy of popularization and application.
KEYWORDS: diabetes mellitus; renal injury; urine glucose; urinary microalbumin

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