不同方式治疗新生儿先天性心脏病合并心力衰竭、肺动脉高压的疗效

晋芙莉，宋文萍，冯爽*

（渭南市妇幼保健院新生儿科，陕西 渭南，714000）

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摘要：

目的 分析新生儿先天性心脏病合并肺动脉高压及心力衰竭经前列地尔脂微球治疗的临床效果。方法 选取我院2017年1月至12月收治的76例新生儿先天性心脏病合并肺动脉高压及心力衰竭患儿作为研究对象，根据不同治疗方式将其分 为研究组（38 例）与对照组（38 例）。对照组行常规治疗，研究组基于常规治疗行前列地尔脂微球治疗。比较两组患儿的治疗 效果。结果 与治疗前比较，两组患者治疗的肺动脉收缩压、左室射血分数、呼吸频率明显改善，且与对照组比较，研究组治疗 后的上述指标明显更优（P<0.05）。与对照组比较，研究组的治疗总有效率明显更高（P<0.05）。结论 新生儿先天性心脏病合并 肺动脉高压及心力衰竭经前列地尔脂微球治疗的临床效果显著，可有效改善临床各项指标，值得推广运用。

关键词：新生儿；先天性心脏病；肺动脉高压；心力衰竭；前列地尔脂微球

中图分类号：R725.4文献标志码：A文章编号：2096-1413(2018)06-0090-02

Clinical effect of different therapy on neonatal congenital heart disease complicated with pulmonary hypertension and heart failure
JIN Fu-li, SONG Wen-ping, FENG Shuang*
(Neonatology Department, Weinan Maternity and Child Health Hospital, Weinan 714000, China)

ABSTRACT: Objective To analyze the clinical effect of prostaglandin microspheres on neonatal congenital heart disease complicated with pulmonary hypertension and heart failure. Methods Seventy -six children with congenital heart disease complicated with pulmonary hypertension and heart failure in our hospital from January to December 2017 were enrolled, they were divided into study group (38 cases) and control group (38 cases) according to different treatment methods. The control group was treated with conventional treatment, while the study group was treated with prostaglandin microspheres on the basis of the conventional therapy. The clinical effects were compared in the two groups. Results Compared with before treatment, the pulmonary artery systolic pressure, left ventricular ejection fraction and respiratory rate of the two groups improved significantly (P<0.05). Compared with the control group, the above indexes of the study group were significantly better (P<0.05). The total effective rate of the study group was significantly higher than that in the control group(P<0.05).Conclusion Prostaglande microspheres has significant clinical effect on neonatal congenital heart disease with pulmonary hypertension and heart failure, which can effectively improve the clinical indicators, it is worth promoting.
KEYWORDS: neonatal; congenital heart disease; pulmonary hypertension; heart failure; prostaglandin microspheres

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