肝硬化患者凝血四项指标检测的临床意义

范红琴

（陕西省韩城市人民医院，陕西渭南，715400）

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摘要：

目的 研究凝血四项指标检测对肝硬化诊断的作用。方法 选取2015年1月至2017年1月我院收治的90例肝硬化患 者作为观察组，选取同时期来我院检查的90 例健康体检者作为对照组，观察两组受检者凝血四项指标检测结果。结果 在两 组的凝血功能四项指标检测中，观察组的APTT、PT、TT 长于对照组，FIB 含量低于对照组，差异均有统计学意义（P<0.05）。ROC 曲线显示，APTT、TT、PT、FIB 的AUC 值分别为0.57、0.47、0.72、0.44，联合诊断的AUC 值为0.77，明显大于凝血四项单项诊断 的AUC 值（P<0.05）。结论 凝血四项指标检测是肝硬化诊断的一种科学有效的方法，通过对病情监测可协助患者尽快康复。

关键词：肝硬化；监测结果；凝血四项指标

中图分类号：R575.2文献标志码：A文章编号：2096-1413(2018)06-0102-02

Clinical significance of four indexes of blood coagulation in patients with liver cirrhosis


FAN Hong-qin
(the People``s Hospital of Hancheng, Weinan 715400, China)

ABSTRACT: Objective To study the effect of four indexes of coagulation in the diagnosis of liver cirrhosis. Methods A total of 90 patients with cirrhosis admitted in our hospital from January 2015 to January 2017 were selected as observation group, another 90 cases of healthy people who received examination in our hospital in the same period were selected as control group. Four indexes of coagulation in the two groups were observed. Results In the detection of four indexes of coagulation, the APTT, PT and TT in the observation group were longer than those in the control group, and the content of FIB in the observation group was lower than that in the control group (P<0.05). The ROC curve shows that the AUC values of APTT, TT, PT and FIB were 0.57, 0.47, 0.72, 0.44 respectively, and the AUC value of combined diagnosis was 0.77, which was significantly higher than those of the four items of single diagnosis of coagulation (P<0.05). Conclusion The detection of four indexes of coagulation is a scientific and effective method in the diagnosis of liver cirrhosis, and it can help the patients to recover as soon as possible by monitoring the condition of the disease.
KEYWORDS: liver cirrhosis; monitoring results; four indexes of coagulation

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