灯盏花素注射液联合曲美他嗪治疗冠心病心绞痛临床分析

邓军喜，李建玲

（1.合阳县中医医院，陕西 渭南，715300；2.陕西省荣复军人第一医院，陕西 宝鸡，721400）

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摘要：

目的 探究对冠心病心绞痛患者采用灯盏花素注射液联合曲美他嗪治疗的临床疗效。方法 选取2012年8月至2015年8月我院收治的94例冠心病心绞痛患者作为研究对象，随机分为观察组和对照组，每组47例。对照组患者给予内科常规治疗，观察组患者在此基础上采用灯盏花素注射液联合曲美他嗪治疗，治疗时间均为30d，对两组患者治疗后的临床效果进行比较。结果治疗前，两组患者的心绞痛发作次数、发病时间比较，差异没有统计学意义（P>0.05）；治疗后，观察组患者心绞痛发作次数、发病时间分别为（0.65±0.32）次、（2.21±0.56）min；对照组患者的心绞痛发作次数、发病时间分别为（1.44±0.51）次、（4.61±1.21）min，组间比较差异具有统计学意义（P<0.05）。对照组患者中，20例显效，12例有效，15例无效，总有效率为 68.09%；观察组患者中，32 例显效，12例有效，3例无效，总有效率为93.62%，差异具有统计学意义（P<0.05）。治疗前，两组患者的血脂水平比较，差异没有统计学意义（P>0.05）；治疗后，两组患者TC、TG、HDL-C、LDL-C 水平均有所改善，且观察组改善情况明显优于对照组，差异均具有统计学意义（P<0.05）。结论 对冠心病心绞痛患者在内科常规治疗基础上采用灯盏花素注射液联合曲美他嗪治疗，效果明显，可减少副反应，提高治愈率，值得在临床中推广与应用。

关键词：冠心病；心绞痛；灯盏花素注射液；曲美他嗪

中图分类号：R;541.4文献标志码：A文章编号：2096-1413(2017)02-0020-02

Clinical analysis of breviscapin injection combined with trimetazidine in the treatment of

 angina pectoris in coronary heart disease

DENG Jun-xi , LI Jian-ling
(1. Heyang County Traditional Chinese Medicine Hospital, Weinan 715300, 2. Shaanxi Rongfu Soldiers First Hospital, Baoji 721400, China）

ABSTRACT: Objective To explore the clinical effect of breviscapine injection combined with trimetazidine in the treatment of angina pectoris in coronary heart disease. Methods Ninety-four cases of patients with angina pectoris of coronary heart disease in our hospital from August 2012 to August 2015 were selected as study objects. All the patients were randomly divided into observation group and control group, with 47 cases in each group. The control group was given conventional medical treatment, while the observation group was treated with breviscapine injection combined with trimetazidine on the basis of control group. After treating for 30 days, the clinical effects of the two groups were observed and compared. Results Before the treatment, the angina attack frequency, onset time of the two groups had no significant difference (P>0.05). After the treatment, the angina attack frequency, onset time in the observation group were (0.65±0.32) min, (2.21±0.56) min, while in the control group they were (1.44±0.51) min, (4.61±1.21)min, the differences between the two groups were statistically significant (P<0.05). In the control group, 20 cases were markedly effective, 12 cases were effective and 15 cases were ineffective, the total effective rate was about 68.09%, while in the observation group, 32 cases were markedly effective, 12 cases were effective and 3 cases were ineffective, the total effective rate was about 93.62%, the difference between the two groups was statistically significant (P<0.05). Before treatment, there was no significant difference in blood lipid level between the two groups (P>0.05). After treatment, the levels of TC、TG、HDL-C、LDL-C in the two groups were obviously improved, and the improvements of observation group were significantly higher than the control group, the differences were statistically significant (P<0.05). Conclusion Breviscapine injection combined with trimetazidine on the basis of conventional medical treatment, has obvious clinical effect for treating patients with angina pectoris of coronary heart disease, which can reduce side effects, improve the cure rate, and is worthy of clinical popularization and application.
KEYWORDS: coronary heart disease; anginapectoris; breviscapine injection; trimetazidine

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