奥曲肽联合兰索拉唑钠治疗急性消化道出血效果观察

万林

（西安交通大学第二附属医院急诊ICU，陕西 西安，710004）

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摘要：

目的 探讨奥曲肽联合兰索拉唑钠急诊治疗急性消化道出血的临床疗效。方法 选取2014 年6 月至2015 年6 月，我院收治的接受急诊治疗急性消化道出血患者60例，随机分为观察组和对照组，每组30例。其中观察组患者采用奥曲肽联合兰 索拉唑钠治疗，对照组患者单纯使用奥曲肽治疗，观察两组患者的止血时间、住院时间及治疗效果。结果 观察组患者在止血 时间和住院时间上明显短于对照组，差异具有统计学意义（P<0.05）。两组治疗总有效率的比较，观察组高于对照组，差异有 统计学意义（P<0.05）。观察组中2例患者出现面色苍白、出汗等症状，予以滴速调整、对症治疗后好转；对照组中3 例患者出 现恶心、呕吐等症状，对症处理后缓解。两组患者均未出现严重不良反应。结论 奥曲肽联合兰索拉唑钠急诊治疗急性消化道出血效果显著，止血速度快，并且安全可靠，不良反应少，有利于患者的疾病恢复，缩短了患者的住院时间，值得广泛使用。

关键词：急性消化道出血；奥曲肽；兰索拉唑钠

中图分类号：R573.2文献标志码：A文章编号：2096-1413(2017)05-0044-02

Clinical observation of octreotide combined with lansoprazole sodium in the

 treatment of acute gastrointestinal hemorrhage
WAN Lin
(Department of Emergency ICU, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China)

ABSTRACT: Objective To investigate the effect of octreotide combined with lansoprazole sodium for emergency treatment of acute gastrointestinal hemorrhage. Methods From June 2014 to June 2015, 60 cases of patients with acute gastrointestinal hemorrhage in our hospital for emergency treatment were randomly divided into observation group and control group, with 30 patients in each group. The observation group was treated with octreotide combined with lansoprazole sodium, while the control group was treated with octreotide only. The hemostasis time, ospitalization time and treatment effects of the two groups were observed. Results The hemostasis time and hospitalization time of the observation group were significantly shorter than those in the control group, the differences were statistically significant (P <0.05). The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). In the observation group, 2 patients presented with pale, sweating and other symptoms, and they were improved after adjusting the drip rate and symptomatic treatment; in the control group, 3 patients had nausea, vomiting and other symptoms, and they were improved after symptomatic treatment. There were no serious adverse reactions occurred in the two groups. Conclusion Octreotide combined with lansoprazole sodium has significant emergency treatment for acute gastrointestinal hemorrhage. It has short hemostasis time, and is safe and reliable with less adverse reaction, which is conducive to the patient's disease recovery. It can shorten the patients' hospital stay, and is worth being widely used.
KEYWORDS: acute gastrointestinal hemorrhage; octreotide; lansoprazole sodium

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