奥曲肽联合奥美拉唑治疗肝硬化上消化道出血的临床疗效观察

陈先华，张宏涛

(陕西省商洛市城关镇卫生院，陕西商洛，726300)

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摘要：

目的 探究肝硬化上消化道出血患者应用奥曲肽和奥美拉唑治疗的效果。方法 选取90例肝硬化上消化道出血患者按治疗方法不同，分成两组，各45例，对照组给予奥曲肽治疗，观察组给予奥曲肽联合奥美拉唑联合治疗，观察两组的治疗效果。结果 观察组总有效率为97.78%，高于对照组80.00%（P<0.05）；观察组住院时间、止血时间明显短于对照组（P<0.05）；观察组术后再次出血发生率为2.22%，低于对照组的15.55%，差异有统计学意义（P<0.05）。结论 肝硬化上消化道出血患者应用奥曲肽和奥美拉唑治疗的疗效确切，可提升治疗有效率，缩短住院时间和止血时间，减少再次出血情况，值得临床推广应用。

关键词：奥曲肽；奥美拉唑；肝硬化上消化道出血

中图分类号：R587.1文献标志码：A文章编号：2096-1413(2017)07-0050-02

Clinical effect of octreotide combined with omeprazole in the treatment of upper gastrointestinal bleeding in liver cirrhosis

CHEN Xian-hua, ZHANG Hong-tao

(Chengguan Town Hospitals, Shangluo 726300, China)

ABSTRACT: Objective To investigate the efficacy of octreotide and omeprazole in the treatment of upper gastrointestinal bleeding in liver cirrhosis. Methods Ninety patients with cirrhosis of upper digestive tract hemorrhage were selected and divided into two groups, with 45 cases in each group. The control group was treated with octreotide alone and the observation group was treated with octreotide combined with omeprazole. The therapeutic effect of the two groups was observed. Results The total effective rate was 97.78% in the observation group, which was higher than 80.00% of the control group (P<0.05);The time hospitalization and hemostasis in the observation group were shorter than those of the control group (P<0.05); The rebleeding rate was 2.22% in the observation group, which was lower than 15.55% of the control group (P<0.05). Conclusion efficacy Octreotide and omeprazole in the treatment of upper gastrointestinal hemorrhage in liver cirrhosis patients has definite, which can improve the effective rate, shorten hospitalization and hemostasis time and reduce the inclence of rebleeding.

KEYWORDS: octreotide; omeprazole; cirrhosis upper gastrointestinal bleeding

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