奥美拉唑联合硫糖铝治疗急性出血性胃炎的疗效及复发观察

姜源，杨湘敏，许怀利，刘卓

（西电集团医院，陕西 西安，710077）

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摘要：

目的 探讨奥美拉唑联合硫糖铝治疗急性出血性胃炎的疗效及复发情况。方法 选择68例急性出血性胃炎患者为研究 对象，采用随机数表法将其分为观察组与对照组，每组34例。对照组患者给予奥美拉唑治疗，观察组患者予以奥美拉唑+硫糖铝治疗。治疗1周后，比较两组患者的治疗效果、出血情况及不良反应发生情况等。结果 观察组治疗总有效率为97.06%，高于对照组的73.53%（P<0.05）；观察组输血量、出血量均较少，止血时间、住院时间均短于对照组（P<0.05）；观察组不同时间再出 血人数显著少于对照组（P<0.05）；观察组复发率、不良反应总发生率均明显低于对照组（P<0.05）。结论 奥美拉唑联合硫糖铝治疗急性出血性胃炎疗效显著，可有效控制患者的出血量、输血量，且用药期间不良反应少，预后复发率低，值得临床广泛应用。

关键词：奥美拉唑；硫糖铝；急性出血性胃炎；复发情况

中图分类号：R573.3文献标志码：A文章编号：2096-1413(2017)11-0006-02

Effect and recurrence of omeprazole combined with sucralfate in the treatment of acute hemorrhagic gastritis
JIANG Yuan, YANG Xiang-min, XU Huai-li, LIU Zhuo

(Xi'an XD Group Hospital, Xi'an 710077, China)

ABSTRACT: Objective To investigate the effect and recurrence of omeprazole combined with sucralfate in the treatment of acute hemorrhagic gastritis. Methods Sixty-eight cases of patients with acute hemorrhagic gastritis were selected and divided into observation group and control group according to random number table, with 34 cases in each group. The control group took omeprazole, while the observation group took omeprazole combined with sucralfate. After one-week treatment, the curative effects, bleeding and adverse reactions of the two groups were compared. Results The total effective rate of the observation group was 97.06%, which was higher than 73.53% of the control group (P <0.05). The transfusion volume,bleeding volume, hemostasis time and hospital stays of the observation group were less than those of the control group (P<0.05). The rebleeding numbers in different time of the observation group was significantly less than that of the control group (P<0.05). The recurrence rate and the incidence of adverse reactions of the observation group were less than those of the control group (P<0.05). Conclusion Omeprazole combined with sucralfate in the treatment of acute hemorrhagic gastritis has significant effect, which can effectively control the bleeding volume and transfusion volume, and has less adverse reactions during medication and low prognostic recurrent rate. It is worthy of wide clinical application.
KEYWORDS: omeprazole; sucralfate; acute hemorrhagic gastritis; recurrence

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