国际标准化比值预测复杂性阑尾炎的临床应用研究

柳英杰

（陕西华县中铁一局集团中心医院外科，陕西 渭南，714101）

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摘要：

目的 寻求急性阑尾炎切除术前更有效的指标，以预测复杂性阑尾炎，便于临床决策。方法 回顾性分析在我院行阑尾切除手术患者260例的临床资料，根据手术结果分为复杂性阑尾炎组（60例）和非复杂性阑尾炎组（200例），分析两组患者 术前的临床化验指标。结果 相较于非复杂性阑尾炎患者，复杂性阑尾炎患者的国际标准化比值（INR）和C反应蛋白（CRP） 明显更高（P<0.01）；进一步行ROC曲线分析，INR和CRP曲线下面积（AUC）分别为0.72和0.80，均高于其他指标。结论 INR在复杂性阑尾炎患者中明显升高，具有较高的临床预测价值。

关键词：阑尾炎；国际标准化比值；C 反应蛋白

中图分类号：R656.8文献标志码：A文章编号：2096-1413(2017)12-0011-03

Clinical application of International normalized ratio in predicting complicated appendicitis
LIU Ying-jie
(Department of Surgery, China Railway First Group Central Hospital in Hua County, Weinan 714101, China)

ABSTRACT: Objective To analyze preoperative laboratory markers that may predict complicated of appendicitis, so as to offer clinical reference. Methods Patients who underwent appendectomy in our hospital were retrospectively recruited. They were divided into complicated appendicitis group (60 cases) and non-complicated appendicitis group (200 cases) according to the operation results, and their preoperative laboratory results were reviewed. Results Compared with non-complicated appendicitis group, the International normalized ratio (INR) and serum C -reactiveprotein (CRP) in the complicated appendicitis group were significantly higher (P<0.01). The ROC curve analysis showed that area under the curve (AUC) of
CRP and INR were 0.80 and 0.72 respectively, which were higher than other indexes. Conclusion INR increases significantly in patients with complicated appendicitis, which is a feasible marker to predicting complicated appendicitis.

KEYWORDS: appendicitis; International normalized ratio; C-reactive protein

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