气管镜联合氨溴索雾化吸入治疗卒中相关性肺炎的临床分析

刘鸿儒

（首都医科大学附属北京友谊医院平谷医院，北京，101200）

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摘要：

目的 探讨分析卒中相关性肺炎患者实施气管镜联合氨溴索治疗的临床价值。方法 选取76例卒中相关性肺炎患者分为联合组和常规组，各38例。常规组接受常规祛痰、抗感染等支持治疗，联合组在常规组基础上实施气管镜联合氨溴索雾化吸入治疗，对比两组患者临床疗效，以及治疗前、后白细胞、C-反应蛋白（CRP）水平。结果 联合组与常规组临床总有效率比较，差异显著（P<0.05）。治疗前，两组患者的白细胞、CRP水平比较，无明显差异（P>0.05）；治疗后，两组患者的白细胞、CRP水平均显著降低（P<0.05），且联合组水平显著低于常规组（P<0.05）。联合组不良反应发生率为5.26%，稍高于常规组的 0.00%，但差异无统计学意义（P>0.05）。结论 在卒中相关性肺炎患者的治疗中采用气管镜联合氨溴索能显著提高疗效，减轻炎症反应，且不良反应较少。

关键词：气管镜；氨溴索；卒中相关性肺炎；炎症反应

中图分类号：R743.3；R563.1文献标志码：A文章编号：2096-1413(2017)12-0089-02

Clinical analysis of bronchoscopy combined with ambroxol in the treatment of stroke associated pneumonia
LIU Hong-ru
(Beijing Friendship Hospital Pinggu Branch, the Affiliated Hospital of Capital Medical University, Beijing 101200, China )

ABSTRACT: Objective To investigate the clinical value of bronchoscopy combined with ambroxol in the treatment of stroke associated pneumonia. Methods Seventy-six cases of patients with stroke associated pneumonia were selected and divided into combination group and routine group, with 38 cases in each group. The routine group was received routine expectorant and anti infection and supportive treatment, while the combination group was given bronchoscopy combined with ambroxol inhalation therapy. The clinical efficacy and levels of leukocyte and C-reactive protein (CRP) before and after treatment were compared. Results There was significant difference on total effective rates between the combination group and the routine group (P<0.05). Before treatment, there were no significant differences on the levels of leukocyte and CRP between the two groups (P>0.05). After treatment, the levels of leukocyte and CRP of the two groups were lower than those before treatment, and the levels of leukocyte and CRP of the combination group were lower than routine group, the differences were statistically significant (P<0.05). The incidence rate of the combination group was 5.26%, which was higher than 0.00% of the routine group, but the difference was not significant (P>0.05). Conclusion Bronchoscopy combined with ambroxol in the treatment of stroke associated pneumonia can significantly improve the clinical effect, reduce inflammation, and it has fewer adverse reactions.
KEYWORDS: bronchoscopy; ambroxol; sroke associated pneumonia; inflammation

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