枯草杆菌二联活菌颗粒辅助抗生素治疗婴幼儿支气管肺炎继发腹泻临床研究

樊华

（陕西省潼关县人民医院儿科，陕西 渭南，714300）

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摘要：

目的 探讨枯草杆菌二联活菌颗粒辅助抗生素治疗婴幼儿支气管肺炎继发腹泻的临床疗效及安全性。方法 选取2013年10月至2016年8月我院收治的184例支气管肺炎继发腹泻婴幼儿，根据治疗方案分为对照组和观察组，各92例。两组均行常规抗生素治疗，在此基础上对照组给予蒙脱石散治疗，观察组给予枯草杆菌二联活菌颗粒治疗，对比两组临床疗效、治疗后3天腹泻缓解情况及止泻时间，并统计两组不良反应发生情况。结果 治疗前，两组排便次数比较，差异不显著（P>0.05）；治疗后，观察组排便次数改善情况明显优于对照组，止泻时间短于对照组，且治疗总有效率为97.83%，高于对照组的90.22%， 差异均有统计学意义（P<0.05）；观察组不良反应发生率为2.17%，与对照组的3.26%比较，差异无统计学意义（P>0.05）。结论 枯草杆菌二联活菌颗粒辅助抗生素治疗婴幼儿支气管肺炎继发腹泻，临床效果显著，有利于缩短患儿止泻时间，安全性较高。

关键词：支气管肺炎；抗生素；继发性腹泻；枯草杆菌二联活菌颗粒

中图分类号：R725.6文献标志码：A文章编号：2096-1413(2017)13-0115-02

Clinical study of double live bacteria of bacillus subtilis pellet auxiliary antibiotic in the treatment of infantile diarrhea secondary to bronchial pneumonia
FAN Hua
(Department of Paediatrics, Tongguan County People s Hospital, Weinan 714300, China)

ABSTRACT: Objective To investigate the clinical effect and safety of bacillus subtilis pellet auxiliary antibiotic in the treatment of infantile diarrhea secondary to bronchial pneumonia. Methods One hundred and eighty-four cases of children with infantile diarrhea secondary to bronchial pneumonia in our hospital from October 2013 to August 2016 were selected and divided into control group and observation group according to the treatment plans, with 92 cases in each group. The two groups were treated with conventional antibiotic therapy. On the basis of this, the control group was given montmorillonite powder, while the observation group was given bacillus subtilis pellet. The clinical effect, diarrhea times and an tidiarrheal time after treatment for 3 days and the adverse reactions of the two groups were compared and analyzed. Results Before treatment, there was no significant difference in diarrhea times between the two groups (P>0.05). After treatment,the diarrhea times of the observation group was better than that of the control group, the antidiarrheal time of the observation group was shorter than of the control group, and the total effective rate of the observation group was 97.83%, which was higher than 90.22% of the control group (P>0.05). The adverse reaction incidence rate of the observation group was 2.17%, which has no statistically significant difference compared with 3.26% of the control group (P>0.05). Conclusion The clinical effect of double live bacteria of bacillus subtilis pellet auxiliary antibiotic in the treatment of infantile diarrhea secondary to bronchial pneumonia is significant, which is beneficial to shortening the time of diarrhea, and has high safety.

KEYWORDS: bronchial pneumonia; antibiotic; diarrhea secondary; double live bacteria of bacillus subtilis pellet

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