三联疗法治疗消化内科慢性萎缩性胃炎的效果分析

赵斌1 ，方鹏2

（1.陕西省宝鸡市高新人民医院消化内科，陕西 宝鸡，721013；2.陕西省柞水县人民医院大内科，陕西 商洛，711499）

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摘要：

目的 探讨消化内科慢性萎缩性胃炎临床规范化治疗的效果。方法 选择2014 年7 月至2015 年8 月来我院就诊的慢性萎缩性胃炎患者80 例，随机分成对照组（40 例）和治疗组（40 例）。对照组患者给予养胃冲剂治疗，治疗组患者在对照组治疗的基础上采用标准三联疗法治疗，即选用奥美拉唑、阿莫西林、克拉霉素联合治疗。两组患者治疗3 周后进行相关检查，比较两组患者的治疗效果。结果 治疗后，治疗组有36 例显效，3 例有效，1 例无效，治疗总有效率为97.5%。对照组有20 例显效，12例有效，8 例无效，治疗有效率为80.0%。治疗组的治疗总有效率明显高于对照组，差异具有统计学意义（P<0.05）。结论 采用奥美拉唑、阿莫西林、克拉霉素联合治疗慢性萎缩性胃炎效果明显，具有较高的临床应用价值。

关键词：内科；慢性萎缩性胃炎；规范治疗

中图分类号：R573.32 文献标志码：A文章编号：2096-1413(2016)25-0060-02

Effect analysis of triple therapy in the treatment of chronic atrophic gastritis in the Digestive Department of Internal Medicine
ZHAO Bin 1, FANG Peng 2
(1. Digestion Department of Internal Medicine, Gaoxin People`s Hospital of Baoji, Baoji 721013; 2. Department of Internal Medicine, People`s Hospital of ZhaShui County, Shangluo 711499, China)

ABSTRACT: Objective To investigate the clinical effect of standardized treatment of chronic atrophic gastritis in the digestive department of internal medicine. Methods Eighty cases of patients with chronic atrophic gastritis in our hospital from August 2015 to July 2014 were randomly divided into control group (n=40) and treatment group (n=40). The control group was treated with Yangwei granule, while the treatment group used omeprazole, amoxicillin and clarithromycin on the basis of the control group. After 3 weeks of treatment, patients in the two groups took relative examination, and the treatment effects were compared in the two groups. Results After treatment, 36 cases were markedly effective, 3 cases were effective, 1 cases were ineffective in the treatment group, and the effective rate was 97.5%. In the control group, 40 cases were markedly effective, 12 cases were effective, 8 cases were ineffective and the effective rate was 80%. The effective rate in the treatment group was significantly higher than that in the control group, the difference was statistically significant (P<0.05). Conclusion The combined therapy of omeprazole, amoxicillin and clarithromycin of chronic atrophic gastritis has a good effect and a high clinical value.
KEYWORDS: department of internal medicine; chronic atrophic gastritis; standardized treatment

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