缩宫素联合米索前列醇治疗产后出血的临床疗效分析

张秋芳

（陕西省商洛市商州区大赵峪社区服务中心，陕西 商洛，726000）

浏览次数：91次 下载次数：333次

摘要：

目的 探究缩宫素联合米索前列醇治疗产后出血的临床疗效。方法 我院选取2010年3月至2015年3月收治的100例产妇，随机分为观察组（50例）和对照组（50例）。对照组产妇给予缩宫素治疗，观察组产妇给予缩宫素联合米索前列醇治疗， 比较两组产妇宫缩恢复时间、产后2h出血量、产后24h出血量。结果 观察组宫缩恢复时间为（9.05±0.95）min，产后2 h出血量为（144.21±33.24）mL，产后24h出血量为（186.20±51.13）mL；对照组宫缩恢复时间为（12.52±1.24）min，产后2 h出血量 为（217.45±42.26）mL，产后24 h出血量为（327.18±55.34）mL，观察组的各项指标均优于对照组，差异具有统计学意义（P< 0.05）。结论 对产后出血的产妇采用缩宫素联合米索前列醇治疗，效果明显，产妇宫缩恢复时间短，产后24 h出血量少，能促进产妇早日康复，值得在临床上进行推广和应用。

关键词：米索前列醇；缩宫素；产后出血

中图分类号：R714.46文献标志码：A文章编号：2096-1413(2016)25-0144-02

Clinical efficacy of oxytocin combined with misoprostol on postpartum hemorrhage
ZHANG Qiu-fang
(Dazhaoyu Community Service Center in Shangzhou District, Shangluo 726000, China)

ABSTRACT: Objective To explore the clinical effect of oxytocin combined with misoprostol in the treatment of postpartum hemorrhage. Methods from March 2010 to March 2015, 100 cases were selected as study objects, and randomly divided into observation group (50 cases) and control group (50 cases). The control group was given oxytocin treatment, the patients in the observation group were given oxytocin combined with misoprostol treatment, compared two groups of patients with uterine recovery time, 2 h postpartum hemorrhage, 24 h postpartum bleeding. Results In the observation group, the uterine recovery time was (9.05±0.95) min, 2 h postpartum hemorrhage was (144.21±33.24) mL, 24 h postpartum hemorrhage was (186.20±51.13) mL; in the control group, the uterine recovery time was (12.52±1.24) min, 2 h postpartum hemorrhage was (217.45±42.26) mL, 24 h postpartum hemorrhage was (327.18±55.34) mL. The observation group was superior to the control group in the comparisons of above indexes, the differences between the two groups had statistical significance (P<0.05). Conclusion For patients with postpartum hemorrhage, oxytocin combined with misoprostol has better effect, with short uterine recovery time, postpartum 24 h less bleeding and less adverse reaction, which is suitable for the clinical application.
KEYWORDS: misoprostol; oxytocin; postpartum hemorrhage

参考文献：
[1] 罗友娣,张文慧,于寿伦,等.米索前列醇联合缩宫素预防剖宫产术后出血的研究[J].国际医药卫生导报,2011,10(12):24-25.
[2] 宋婷婷,代秀云,冷海娜.缩宫素联合米索前列醇预防产后出血30例临床观察[J].中国当代医药,2011,18(5):53-54.
[3] 高燕,但阳,刘菊莲,等.米索前列醇预防产后出血高危因素效果观察[J].中国医学创新,2011,8(14):46-48.
[4] 卢彩珠,罗秀霞.米索前列醇预防产后出血的临床观察[J].中外医学研究,2012,10(33):14-15.
[5] 赵晓颖.缩宫素联合米索前列醇治疗产后出血50 例的临床效果分析[J].中国妇幼保健,2014,20(5):807-808.