糖尿病足复发感染的病原菌种类及药敏特征分析

李兰英，张红英

（陕西省渭南市第二医院，陕西 渭南，714000）

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摘要：

目的 探讨糖尿病足复发感染的病原菌种类及其药敏特征。方法 选择2014年9月至2016年9月我院收治的100例糖尿病足感染患者，均行踝肱指数（ABI）测量，对创面分泌物送检标本行常规细菌培养与药物敏感试验，分析病原菌种类及药敏特征。结果 糖尿病足复发感染标本中，42.50%为革兰阳性菌株，49.17%为革兰阴性菌株；糖尿病足复发感染病原菌耐药性中，革兰阳性球菌对青霉素、红霉素耐药严重，对环丙沙星、庆大霉素、克林霉素较为敏感，对万古霉素未出现耐药情况；革兰阴性菌对头孢氨芐、头孢噻肟、红霉素、头孢他啶耐药严重，对诺氟沙星、美罗培南、庆大霉素较为敏感，对帕尼培南未见耐药性。结论 糖尿病足感染患者病原菌种类较多，且对常规抗菌药物存在一定耐药率，需严格合理应用抗生素。

关键词：糖尿病足；复发感染；病原菌；药敏特征

中图分类号：R587.2文献标志码：A文章编号：2096-1413(2017)26-0112-02

Analysis of pathogenic bacteria species and their drug sensitivity characteristics of recurrent infection in diabetic foot
LI Lan-ying, ZHANG Hong-ying
(the Second Hospital of Weinan, Weinan 714000, China)

ABSTRACT: Objective To analyze the pathogenic bacteria species and their drug sensitivity characteristics of recurrent infection in diabetic foot. Methods A total of 100 patients with diabetic foot admitted in our hospital from September 2014 to September 2014 were selected as the study objects. All the patients underwent ankle brachial index (ABI) test, the wound secretion inspection specimens conventional bacterial culture and drug sensitivity were tested, and the pathogenic bacteria species and their drug sensitivity characteristics were analyzed. Results In diabetes foot recurrence infection specimens, 42.50% was gram positive strains, 49.17% was gram negative strains. In the drug resistance of pathogenic bacteria in recurrent infection of diabetic foot, gram positive strains were highly resistant to penicillin and erythromycin, sensitive to ciprofloxacin, gentamicin and clindamycin, and no resistance to vancomycin; gram negative strains were highly resistant to keflex, erythromycin, cefotaxime and ceftazidime, sensitive to norfloxacin, meropenem, gentamycin, and no resistance to panipenem. Conclusion There are many kinds of pathogenic bacteria in diabetic foot infections, which have a certain rate of resistance to conventional antibiotics, and strict and rational use of antibiotics is needed.
KEYWORDS: diabetic foot; recurrent infection; infection bacteria; drug sensitivity characteristics

参考文献：
[1] 关小宏,杨彩哲,吴石白.糖尿病足感染的特点与治疗[J].中华医院感染学杂志,2012,22(19):4237-4239.
[2] 刘剑烽,冉建民,刘薇,等.糖尿病足溃疡面细菌培养及药敏特点分析[J].临床医学工程,2012,19(1):32-35.
[3] 糖尿病足(肢端坏疽)检查方法及诊断标准(草案)[J].中国糖尿病杂志,1996,4(2):126.
[4] 肖婷.糖尿病足溃疡恶化和截肢相关因素分析[D].西安:第四军医大学,2010.
[5] 柳迎昭,王丽,陈建国.糖尿病足感染患者病原菌分布及耐药性分析[J].山西医药杂志,2014,43(19):2264-2266.
[6] 邓晓龙,肖立虎,陈大伟,等.糖尿病足溃疡伴感染无菌棉拭子擦拭 取样及深部组织活检取样细菌培养的一致性研究[J].中国糖尿病杂志,2014,4(7):504-508.
[7] 陈芳,李素梅,王炜,等.糖尿病足患者足部创面感染的病原菌分布及药敏结果分析[J].山东医药,2016,56(30):49-51.