泮托拉唑钠治疗消化溃疡合并消化道出血临床效果分析
张格利
（周至县人民医院消化内科，陕西 西安，710400）
浏览次数：77次 下载次数：393次
摘要：
目的 对泮托拉唑钠治疗消化溃疡合并消化道出血的临床治疗效果进行分析。方法 选取我院2015年5月至2016年11月收治的84例消化溃疡合并消化道出血患者，采用随机的方法将患者分为参照组与研究组，各42例，参照组患者使用奥 美拉唑进行治疗，研究组患者使用泮托拉唑钠进行治疗，对比两组患者的临床治疗效果以及不良反应发生情况。结果 研究 组患者的临床治疗总有效率为95.24%，不良反应发生率为2.38%；参照组患者的临床治疗总有效率为73.81%，不良反应发 生率为21.43%；对比两组患者的临床效果以及不良反应发生情况，研究组患者治疗总有效率明显高于参照组，且不良反应发生率明显低于参照组（P<0.05）。结论 对消化溃疡合并消化道出血患者使用泮托拉唑钠进行治疗能够取得非常理想的效果，使患者的病情得到了有效改善，大大提高了患者的治疗有效性，并且降低了患者的不良反应发生率，有助于帮助患者尽早恢复到正常生活，值得加以推广运用。
关键词：消化溃疡合并消化道出血；泮托拉唑钠；奥美拉唑
中图分类号：R573.1文献标志码：A文章编号：2096-1413(2017)28-0047-02
Clinical efficacy analysis of pantoprazole sodium in the treatment of peptic ulcer together with gastrointestinal hemorrhage
ZHANG Ge-li
(Department of Gastrdogy, Zhouzhi County People``s Hospital, Xi``an 710400, China)
ABSTRACT: Objective To analyze the clinical efficacy of pantoprazole sodium in the treatment of peptic ulcer together with gastrointestinal hemorrhage. Methods From May 2015 to November 2016, 84 cases of patients with peptic ulcer and gastrointestinal hemorrhage treated in our hospital were selected and randomly divided into control group and research group, with 42 cases in each group. The patients in the control group were treated with omeprazole, while the research group used pantoprazole sodium. The clinical therapeutic efficacy and adverse reactions of the two groups were compared. Results The clinical total effective rate of the research group was 95.24% and the incidence of adverse reactions was 2.38% ; the total effective rate of the control group was 73.81% and the incidence of adverse reactions was 21.43% ; compared with the control group, the total effective rate of the research group was significantly higher and the incidence of adverse reactions was significantly lower (P<0.05). Conclusion Pantoprazole sodium has the ideal curative effect in the treatment of peptic ulcer with gastrointestinal hemorrhage and effectively improve the patients`` condition, can not only improve clinical effective rate and reduce adverse reactions but also help patients return to normal life as soon as possible, which is worthy of promotion and application.
KEYWORDS: peptic ulcer together with gastrointestinal hemorrhage; pantoprazole sodium; omeprazole
参考文献：
[1] 马淑云,孙国辉,张婕,等.肝硬化非静脉曲张消化道出血临床特征 [J].胃肠病学和肝病学杂志,2015,24(11):1324-1326.
[2] 陈治水,危北海,张万岱,等.溃疡性结肠炎中西医结合诊疗指南(草案)(中国中西医结合学会消化系统疾病专业委员会,2010,西昌)[J].中 国中西医结合消化杂志,2011,19(1):61-65.
[3] 李继军,尚建强,刘作勤,等.肝癌肝动脉-门静脉瘘并消化道出血的介入治疗[J].介入放射学杂志,2011,20(2):120-122.
[4] 俞军,张武,张珉,等.肝移植治疗门静脉高压上消化道出血的疗效分析[J].中国普外基础与临床杂志,2013,20(1):24-28.
[5] 汪官富,徐颖鹤,苏杭,等.双歧杆菌四联活菌片联合三联疗法治疗幽门螺杆菌阳性消化性溃疡的疗效[J].中华医院感染学杂志,2013,23(9):2074-2076.
[6] 邱洪,陈珏,杨跃进,等.经皮冠状动脉介入治疗后消化道出血的治疗经验[J].中国循环杂志,2013,28(4):250-253.
[7] 杨欣艳,李恕军,刘飞,等.急性非静脉曲张性上消化道出血临床分析[J].胃肠病学和肝病学杂志,2012,21(8):727-729.