血清BNP、HCY、hs-CRP及心肌三联在急性心肌梗死中的诊断价值

苏周

（西安兵器工业五二一医院，陕西 西安，710065）

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摘要：

目的 分析血清BNP、HCY、hs-CRP及心肌三联在急性心肌梗死（AMI）中的诊断价值。方法 收集AMI 患者和同期行体检的健康者各50例，分别为AMI组和对照组，检测两组血清BNP、cTnT、CK-MB、Mb、HCY及hs-CRP水平。结果 AMI 组血清中的cTnT、CK-MB、Mb、BNP、HCY、hs-CRP水平均明显高于对照组（P<0.05）。6项指标联合检测AMI 诊断效率的特异度、灵敏度阳性预测值和阴性预测值分别为80.00%、100.00%、83.33%及100.00%。结论 联合检测6项血清学指标的诊断效率相对高于单项指标，同时血清中hs-CRP、HCY、BNP水平的升高，对AMI患者的预后和复发有一定的指 导意义。

关键词：心肌梗死；BNP；cTnT；CK-MB；Mb；HCY；hs-CRP

中图分类号：R542.2文献标志码：A文章编号：2096-1413(2017)30-0021-02

Diagnostic value of serum BNP, HCY, hs-CRP and myocardial triad in patients with myocardial infarction
SU Zhou
(No.521 Hospital of Xi``an Ordnance Industry, Xi``an 710065, China)

ABSTRACT: Objective To analyze the diagnostic value of serum BNP, HCY, hs-CRP and myocardial triad in patients with acute myocardial infarction (AMI). Methods Fifty AMI patients (AMI group) and Fifty healthy subjects (control group) were enrolled in the study. The levels of serum BNP, cTnT, CK -MB, Mb, HCY and hs -CRP in the two groups were detected. Results The levels of serum cTnT, CK-MB, Mb, BNP, HCY and hs-CRP in the AMI group were obviously higher than those in the control group (P<0.05). The specificity, sensitivity, positive predictive value and negative predictive value of the combined detection of 6 indicators for diagnosis of AMI were 80.00%, 100.00%, 83.33% and 100.00% respectively. Conclusion The diagnostic efficiency of combined detection of 6 serum markers is relatively higher than single index. At the same time, with the increase of levels of serum hs-CRP, HCY and BNP, which have certain guiding significance for the prognosis and recurrence of patients with AMI.
KEYWORDS: acute myocardial infarction (AMI); BNP; cTnT; CK-MB; Mb; HCY; hs-CRP

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