幽门螺杆菌感染与反流性食管炎的相关性分析

唐毅，汪小军，方宁，李思源

（陕西省安康市汉滨区第二医院，陕西 安康，725021）

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摘要：

目的 探讨幽门螺杆菌感染与反流性食管炎的相关性。方法 选择2011 年3 月至2016 年3 月在我院收治的反流性食管炎 患者95 例为研究对象，所有患者均经胃镜检查确诊为反流性食管炎。按照中华医学会消化病学分会2000 年制定的Tygatat 分级标准，将95 例反流性食管炎患者分为Ⅰ～Ⅴ级，Ⅰ级28 例，Ⅱ级39 例，Ⅲ级21 例，Ⅳ级4 例，Ⅴ级3 例。比较不同分级 的反流性食管炎患者幽门螺杆菌感染发生率。结果 本研究95 例反流性食管炎患者中，共有缘缘 例患者发生幽门螺杆菌感 染，总感染率为57.89%(55/95)；反流性食管炎分级Ⅰ级的幽门螺杆菌感染率为67.86%（19/28），Ⅱ级为53.85%（21/39），Ⅲ级 为57.14%（12/21），Ⅳ级为50.00%（2/4），Ⅴ级为33.33%（1/3）；随着反流性食管炎患者疾病严重程度的增加，幽门螺杆菌感 染的发生率逐渐降低。结论 反流性食管炎患者的严重程度随幽门螺杆菌感染发生率的升高而降低，两者之间呈负相关。

关键词：幽门螺杆菌；感染；反流性食管炎

中图分类号：R571文献标志码：A文章编号：2096-1413(2017)36-0042-02

Analysis of the correlation between Helicobacter pylori infection and reflux esophagitis
TANG Yi, WANG Xiao-jun, FANG Ning, LI Si-yuan
(Secondary Hospital of Hanbin District in Ankang City, Ankang 725021, China)

ABSTRACT: Objective To study the correlation between Helicobacter pylori infection and reflux esophagitis. Methods Ninety-five cases of reflux esophagitis patients admitted in our hospital from March 2011 to March 2016 were selected and diagnosed as the reflux esophagitis by endoscopy. According to the Tygatat classification criteria established by the gastroenterology branch of Chinese Medical Association in 2000, 95 reflux esophagitis patients were divided into Ⅰ～Ⅴ grade, 28 cases of gradeⅠ, 39 cases of gradeⅡ, 21 cases of grade Ⅲ, 4 cases of grade Ⅳ, 3 cases of gradeⅤ. Helicobacter pylori infection rates in patients with reflux esophagitis of different grades were compared. Results In 95 reflux esophagitis patients, there were 55 patients infected with Helicobacter pylori, the Helicobacter pylori total infection rate was 57.89%; the infection rate in grade I reflux esophagitis was 67.86% (19/28), which in grade II was 53.85% (21/39), in grade III was 57.14% (12/21), in grade IV was 50.00% (2/4), and in grade V was 33.33% (1/3). With the increase of the severity of reflux esophagitis, the incidence of Helicobacter pylori infection decreased gradually. Conclusion The severity of reflux esophagitis decrease with the increase of the incidence of Helicobacter pylori infection, and there is a negative correlation between them.
KEYWORDS: Helicobacter pylori; infection; reflux esophagitis

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