阿奇霉素与红霉素治疗儿童肺炎的临床效果及不良反应

王有良

（陕西省潼关县医院儿科，陕西 渭南，714399）

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摘要：

目的 分析阿奇霉素与红霉素治疗儿童肺炎的临床效果及不良反应。方法 选取我院2013 年2 月至2016 年2 月收治的120 例肺炎患儿为研究对象，根据不同治疗方法分为对照组（n=55）和观察组（n=65），分别采取红霉素和阿奇霉素进行治疗。比较 两组患者的临床效果、临床症状消失时间及不良反应发生情况。结果 观察组患儿的总有效率为96.9%，对照组患儿的总 有效率为94.5%，两组患儿治疗总有效率比较，差异无统计学意义（P>0.05）；观察组患儿的体温降低、咳嗽消失及肺部音消失时间均短于对照组（P<0.05）；观察组患儿不良反应总发生率明显低于对照组（P<0.05）。结论 对儿童肺炎采用阿奇霉 素进行治疗，能有效缩短临床症状消失时间，安全可靠，值得临床大力推广应用。

关键词：儿童肺炎；阿奇霉素；红霉素

中图分类号：R739.4文献标志码：A文章编号：2096-1413(2017)36-0108-02

Clinical effect and adverse reactions of azithromycin and erythromycin in the treatment of pneumonia in children
WANG You-liang
(Pediatrics Department, Tongguan County Hospital, Weinan 714399, China)

ABSTRACT: Objective To analyze the clinical effect and adverse reactions of azithromycin and erythromycin in the treatment of pneumonia in children. Methods From February 2013 to February 2016, 120 cases of children with pneumonia were selected and divided into control group (n=55) and observation group (n=65) according to different treatment methods, and were treated with erythromycin and azithromycin respectively. The clinical effects, clinical symptoms disappearance time and adverse reactions were compared between the two groups. Results The total effective rate of the observation group was 96.9%, and that of the control group was 94.5%, there was no significant difference in total effective rate between the two groups (P>0.05). The disappearance time of hypothermia, cough and pulmonary rales of the observation group were shorter than those of the control group (P<0.05). The total incidence rate of adverse reactions of the observation group was lower than that of the control group (P<0.05). Conclusion Azithromycin used in the treatment of children with pneumonia can significantly shorten the clinical symptoms disappearance time, it is safe and reliable, which is worthy of clinical application and promotion.
KEYWORDS: pneumonia in children; azithromycin; erythromycin

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