重组牛碱性成纤维细胞生长因子滴眼液联合玻璃酸钠滴眼液治疗青光眼滤过术后干眼症的效果

王雅君

（西安电子科技大学医院，陕西 西安，710071）

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摘要：

目的 探究重组牛碱性成纤维细胞生长因子滴眼液联合玻璃酸钠滴眼液治疗青光眼滤过术后干眼症的临床效果。方法 选取我院2016 年1 月至2016 年12 月收治的126 例青光眼滤过术后干眼症患者为研究对象，采用数字表法随机分为观察 组和对照组，各63 例。对照组患者采用玻璃酸钠滴眼液治疗，观察组患者则采用重组牛碱性成纤维细胞生长因子滴眼液联 合玻璃酸钠滴眼液治疗。比较两组的临床疗效。结果 观察组患者的治疗总有效率显著高于对照组（P<0.05）；治疗后，观察组泪膜破裂时间、泪液分泌试验、角膜荧光染色评分均明显改善，且优于对照组（P<0.05）。结论重组牛碱性成纤维细胞生长因 子滴眼液联合玻璃酸钠滴眼液治疗青光眼滤过术后干眼症的疗效确切。

关键词：青光眼滤过术后干眼症；重组牛碱性成纤维细胞生长因子；玻璃酸钠

中图分类号：R777.34文献标志码：A文章编号：2096-1413(2018)02-0044-02

Effect of recombinant bovine basic fibroblast growth factor gutta combined with sodium hyaluronate gutta in the treatment

of dry eye after glaucoma filtering surgery
WANG Ya-jun
(the Hospital of Xidian University, Xi``an 710071, China)

ABSTRACT: Objective To investigate the clinical efficacy of recombinant bovine basic fibroblast growth factor gutta combined with sodium hyaluronate gutta in the treatment of dry eye after glaucoma filtering surgery. Methods From January 2016 to December 2016, 126 patients with dry eye after glaucoma filtering surgery were enrolled in this study, and randomly divided into observation group and control group, with 63 cases in each group. The patients in the control group were treated with sodium hyaluronate gutta, the patients in the observation group were treated with recombinant bovine basic fibroblast growth factor gutta combined with sodium hyaluronate gutta. The clinical effects between the two groups were compared. Results The total effective rate of the observation group was significantly higher than that of the control group (P<0.05). After treatment, the tear film rupture time, tear secretion test and the score of corneal fluorescence staining of the observation group significantly improved, and those of the observation group were better than the control group (P<0.05). Conclusion The effect recombinant bovine basic fibroblast growth factor gutta combined with sodium hyaluronate gutta in the treatment of dry eye after glaucoma filtering surgery is obvious.
KEYWORDS: dry eye after glaucoma filtering surgery; recombinant bovine basic fibroblast growth factor; sodium hyaluronate

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