低分子肝素预防术后肺栓塞效果研究

黄以庭，刘军，冯雅薇，李芸

（1.中山大学附属第三医院粤东医院麻醉科，广东 梅州，514000；2.中山大学附属第三医院麻醉科，广东 广州，510630；

浏览次数：126次 下载次数：496次

摘要：

目的 探讨低分子肝素预防术后肺栓塞的临床效果。方法 选取我院2014年7月至2015年10月收治的98例胸部肿瘤患者为研究对象，采取随机数字表法将其分为研究组（49例）与参照组（49例），两组患者均给予手术治疗，研究组术后第1天开始皮下注射低分子肝素预防肺栓塞，对比两组患者术后肺部栓塞发生率、其他并发症发生情况及患者满意度。结果 治疗后，研究组患者肺部栓塞发生率为0.00%，其他并发症发生率为2.04%，均显著低于参照组的12.24%、14.29%；研究组患者的治疗满意度为95.92%，显著高于参照组的83.67%（P<0.05）。结论 术后早期应用低分子肝素，可预防肺栓塞发生，降低并发症发生率，安全可行，且患者满意度高，临床应用价值高，可推广应用。

关键词：胸部肿瘤；低分子肝素；肺栓塞；满意度

中图分类号：R655；R563.5文献标志码：A文章编号：2096-1413(2017)06-0044-02

The effect of low molecular weight heparin in prevention of pulmonary embolism
HUANG Yi-ting 1, LIU Jun 2, FENG Ya-wei 2, LI Yun 3
(1. Department of Anesthesiology, the Third Affiliated Hospital of Sun Yat-Sen University Yuedong Hospital, Meizhou 514000; 2.Department of Anesthesiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630;

3. Department of Thoracic Surgery, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China)

ABSTRACT：Objective To explore the effect of low molecular weight heparin in the prevention of postoperative pulmonary embolism. Methods Ninety -eight cases of chest tumor patients from July 2014 to October 2015 in our hospital were selected as the research objects, and they were divided into research group and reference group, according to random digital table method, with 49 cases in each group. All the patients in the two groups were received surgery treatment. After that, the patients in research group were received subcutaneous injection of low molecular weight heparin to prevent pulmonary embolism from the first day of the operation. The occurrence rate of pulmonary embolism, other complication, and the satisfaction rate of the patients in the two groups were compared. Results After treatment, the occurrence rate of pulmonary embolism in research group was 0.00%, and the occurrence rate of other complication was 2.04%, which were both significantly lower than 12.24% and 14.29% in the reference group. The satisfaction rate of the patients in research group was 95.92%, which was significantly higher than 83.67% in the reference group (P<0.05). Conclusion Early use of low molecular weight heparin for patients after surgery can be used to decrease the occurrence rate of pulmonary embolism and complication rates, and to improve the satisfaction rate of the patients. It has high clinical application value and can be popularized and applied.
KEYWORDS：thoracic cancer; low molecular weight heparin; pulmonary embolism; satisfaction rate

参考文献：
[1] 杨冬梅.胸部肿瘤手术后急性肺栓塞的护理[J].医学美学美容(中旬刊),2014,8(6):255.
[2] 刘阳,张为迪,刘希斌,等.单孔全胸腔镜手术在胸部肿瘤治疗中的应用[J].山东医药,2016,56(10):72-73.
[3] 王新荣,唐华,袁才霞,等.胸部肿瘤患者开胸术后下肢深静脉血栓形成的预见性护理[J].中国癌症防治杂志,2015,8(3):226-228.
[4] 刘颖.胸部肿瘤病人开胸术后下肢深静脉血栓的预防性护理[J].中国保健营养,2015,25(14):223-224.
[5] 季凤俊,陆松华,杨长刚,等.低分子肝素在胸部肿瘤围手术期的应用价值[J].北方药学,2014,8(9):88-89.
[6] 朱金才.低分子肝素钙治疗放射性肺炎28例[J].医学信息,2013,13(24):235.
[7] 段林灿,钱可宝,巫正伟.低分子肝素对胸部肿瘤术后血栓性疾病预防作用的研究[J].重庆医学,2013,42(10):1119-1121.