中国学术期刊网络出版总库入编期刊
CNKI中文期刊全文数据库全文收录期刊
中国核心期刊(遴选)数据库全文收录期刊
万方数据——数字化期刊群收录期刊
中文科技期刊数据库全文收录期刊

主管:陕西省卫生健康委员会
主办:西安心身医学研究所
   西安交通大学第一附属医院
国际标准刊号:ISSN2096—1413
国内统一刊号:CN61—1503/R

胺碘酮治疗心衰合并心律失常的临床效果

张改过

(三原县红原医院内科,陕西 咸阳,713800)

浏览次数:89次 下载次数:416次

摘要:

目的 分析胺碘酮治疗心衰合并心律失常疾病的临床效果。方法 随机选取我院收治的72例心衰合并心率失常患者, 随机分为对照组和观察组,每组36 例。对照组患者采用常规疗法,观察组患者在常规疗法的基础上采用胺碘酮治疗,对比两组患者的心功能和心率失常改善情况,以及治疗前、后的心电图QTC间期和心率变化。结果 观察组患者的心功能及心律失 常临床总有效率分别为83.33%、77.78%,明显高于对照组的66.67%、66.67%,差异具有统计学意义(P<0.05);治疗后,两组患者的心电图QTC间期和心率均有明显改善,且观察组明显优于对照组,差异具有统计学意义(P<0.05)。结论 胺碘酮治疗心衰合并心律失常具有非常好的临床效果,能够有效改善患者的心功能及心律失常症状。

关键词:胺碘酮;心衰;心律失常

中图分类号:R541.7文献标志码:A文章编号:2096-1413(2017)19-0017-02

    Clinical effect of amiodarone in the treatment of heart failure complicated with arrhythmia
    ZHANG Gai-guo
    (Department of Internal Medicine, Hongyuan Hospital of Sanyuan County, Xianyang 713800, China)

    ABSTRACT: Objective To analyze the clinical effect of amiodarone in the treatment of heart failure complicated with arrhythmia. Methods Seventy-two heart failure complicated with arrhythmia patients admitted in our hospital were selected and ramdomly divided into control group and observation group, with 36 cases in each group. The control group received routine treatment, and the observation group accepted amiodarone on the basis of the control group. The heart function, improvement of arrhythmia, QTC interval of ECG before and after treatment and heart rate of the two groups were compared. Results The total effective rates of heart function and improvement of arrhythmia in the observation group were 83.33% and 77.78% respectively, which were higher than 66.67% and 66.67% in the control group (P<0.05). After treatment, the QTC interval of ECG and heart rate of the two groups improved, and those of the observation group were better than the control group (P<0.05). Conclusion Amiodarone in the treatment of heart failure complicated with arrhythmia has significant clinical effect, which can effectively improve the heart function and arrhythmia symptoms of the patients.

    KEYWORDS: amiodarone; heart failure; arrhythmia

    参考文献:
    [1] 李中华.胺碘酮治疗心衰合并心律失常患者的临床分析[J].中国实用医药,2013,8(20):188-189.
    [2] 王瑞源,李文斌.胺碘酮治疗心衰合并快速型心律失常患者的疗效观察与护理[J].海南医学,2010,21(21):150-151.
    [3] 何永祥.胺碘酮治疗心衰合并心律失常患者的临床效果[J].中国社区医师,2015,31(12):19,21.
    [4] 邱伟林.胺碘酮治疗心衰合并心律失常患者的临床疗效以及护理效果研究[J].深圳中西医结合杂志,2015,25(9):34-36.
    [5] 许波.胺碘酮治疗心衰合并心律失常患者的临床研究[J].中国卫生标准管理,2015,6(13):107-108.
    [6] 殷淑娟.厄贝沙坦联合胺碘酮治疗慢性心力衰竭并发室性心律失常42例的疗效观察[J].航空航天医学杂志,2010,21(8):1380-1381.
    [7] 金迪.胺碘酮治疗慢性心力衰竭并发室性心律失常56 例临床分析[J].中国卫生标准管理,2015,6(2):57-58.
    [8] 高尚.胺碘酮联合稳心颗粒治疗心衰合并心律失常的临床观察[J]. 中国继续医学教育,2015,7(5):217-218.
    [9] CHRYSANT SG,CHRYSANT GS.The pleiotropic effects of angiotensin receptor blockers[J].J Clin Hypertens (Greenwich),2006,8(4): 261-268.
    [10] ANDO H,USHIJIMA K,HOSOHATA K,et al.Relationship between the receptor occupancy profile and pleiotropic effects of angiotensin II receptor blockers[J].Br J Clin Pharmacol,2013,75(2):415-422.
    [11] KAJIYA T,HO C,WANG J,et al.Molecular and cellular effects of azilsartan: a new generation angiotensin II receptor blocker[J].J Hypertens,2011,29(12):2476-2483.
    [12] 李小卫.胺碘酮联合稳心颗粒治疗心衰合并心律失常的临床疗效[J].当代医药论丛,2013,11(10):308-309.
    [13] 裴丽峰.胺碘酮治疗心力衰竭合并心律失常的效果观察[J].中国卫生标准管理,2015,6(2):64-65.

上一篇雷贝拉唑与奥美拉唑治疗反流性食管炎临床效果比较

下一篇以他汀类为基础的降脂药物联合应用的不良反应分析