阿奇霉素序贯疗法治疗小儿支原体肺炎的疗效分析

刘振冬1 ，郑志新2

（陕西省宝鸡市妇幼保健院：1.药局；2.儿科，陕西 宝鸡，721000）

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摘要：

目的 探析对小儿支原体肺炎病症予以阿奇霉素序贯疗法治疗的临床效果。方法 选取我院收治的小儿支原体肺炎患 儿84 例，按照双盲法将其分为对照组和研究组，每组42例。对照组采用匹多莫德颗粒治疗，研究组采用阿奇霉素序贯疗法， 比较两组患儿的治疗效果、临床指标情况和不良反应发生情况。结果 研究组患儿的治疗总有效率为90.48%，明显高于对照 组患儿的73.81%，差异具有统计学意义（P<0.05）；研究组患儿的咳嗽消失时间、音消失时间、退热时间均短于对照组患儿， 差异具有统计学意义（P<0.05）；研究组患儿的不良反应发生率为11.90%，明显低于对照组患儿的33.33%，差异具有统计学 意义（P<0.05）。结论 对小儿支原体肺炎实施阿奇霉素序贯疗法治疗，不仅能降低患儿的不良反应发生率，缓解患儿的临床指标情况，还能加快患儿康复。

关键词：小儿支原体肺炎；阿奇霉素序贯疗法；匹多莫德颗粒

中图分类号：R725.6 文献标志码：A文章编号：2096-1413(2017)20-0086-02

Efficacy of azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children
LIU Zhen-dong 1, ZHENG Zhi-xin 2
(1. Pharmacies; 2. Department of Pediatrics, Baoji Maternal and Child Health Care Hospital, Baoji 721000, China)

ABSTRACT: Objective To explore the clinical effect of azithromycin sequential therapy in the treatment of mycoplasma pneumonia in children. Methods Eighty-four cases of children with mycoplasmal pneumonia treated in our hospital were selected and divided into control group and study group according to the double -blind method, with 42 cases in each group. The control group was treated with pidotimod granules, and the study group was treated with azithromycin sequential therapy. The therapeutic effects, clinical indexes and adverse reactions of the two groups were compared. Results The total effective rate of the study group was 90.48%, which was significantly higher than 73.81% of the control group (P<0.05). The cough disappearance time, rale disappearance time and fever time in the study group were shorter than those in the control group (P<0.05). The incidence of adverse reactions in the study group was 11.90%, which was significantly lower than 33.33% in the control group (P <0.05). Conclusion The treatment of mycoplasma pneumonia in children with azithromycin sequential therapy can not only reduce the incidence of adverse reactions, alleviate the clinical indicators of children, but also speed up the rehabilitation of children.
KEYWORDS: children with mycoplasma pneumonia; azithromycin sequential therapy; pidotimod granules

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