药师临床干预前后儿科抗生素应用不合理对比分析

芦小霞，王娟

（渭南市第一医院，陕西 渭南，714000）

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摘要：

目的 探讨药师临床干预前、后儿科抗生素应用不合理的情况，为临床合理选择抗生素提供参考。方法 选取2015年1月至2015年12月在我院诊治的患儿1 800 例，将2015 年1 月至2015 年6 月收治的未干预的1 000 例患儿设为未干预组， 将2015 年7月至2015年12月收治的干预的800 例患儿设为干预组，记录两组患儿的治疗效果及抗生素不合理使用情况。结果 干预组的治疗总有效率为98.5%，高于未干预组的92.2%（P<0.05）；干预组患儿的抗生素不合理使用率为1.5%，明显低于未干预组的5.8%（P<0.05）。不合理使用抗生素的70 例患儿中，用法不合理34例、用量不合理16例、配药不合理12例、溶媒选择不合理8 例。结论 儿科抗生素应用不合理情况比较常见，药师临床干预能减少儿科抗生素应用不合理情况，提高治疗疗效。

关键词：药师；抗生素；不合理使用；配药不合理

中图分类号：R969.3文献标志码：A文章编号：2096-1413(2017)20-0090-02

Comparison analysis of unreasonable usage of antibiotics before and after the clinical intervention by pharmacist
LU Xiao-xia, WANG Juan
(the First Hospital of Weinan, Weinan 714000, China)

ABSTRACT: Objective To discuss the unreasonable usage of anti biotics before and after the clinical intervention by pharmacist, and provide reference for selecting antibiotics on clinical. Methods A total of 1 800 cases of children diagnosed and treated in our hospital from January 2015 to December 2015 were selected. From January 2015 to June 2015, 1 000 non intervention children were treated as no intervention group. From July 2015 to December 2015, 800 intervention children were treated as intervention group. The treatment effect and irrational use of antibiotics were recorded in the two groups. Results The total effective rate of the total intervention group was 98.5%, which was higher than 92.2% of the no intervention group (P<0.05). The irrational use rate of antibiotics in the intervention group was 1.5%, which was significantly lower than 5.8% in the no intervention group (P<0.05). Among 70 unreasonable usage cases, there were 34 cases of methods unreasonable, 16 cases of doses unreasonable, 12 cases of prescription unreasonable, and 8 cases of solvent selection unreasonable. Conclusion It is common that unreasonable usage of antibiotics in pediatrics. However, clinical intervention by pharmacist can reduce the unreasonable usage situation in pediatrics, and improve the clinical efficacy.
KEYWORDS: pharmacist; antibiotics; unreasonable usage; unreasonable prescription

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